genetic codeRNA worldprogeneprotein worldlipid worldThe origin of genetic code and translation system is probably the central and most difficult problem in the investigations on the origin of life and one of the
and P. V. Baranov. 2007 . Duality in the genetic code. Nature 448:7157 1004 – 1005 .Atkins, John F./Baranov, Pavel V. (2007): Translation: Duality in the genetic code. In: Nature 448, 1004-1005.Atkins JF, Baranov PV. Translation: duality in the genetic code. Nature, 2007; 448...
Dunham, Mechanisms of mRNA frame maintenance and its subversion during translation of the genetic code, Biochimie 114 (2015) 90-96.Dunkle JA, Dunham CM. 2015. Mechanisms of mRNA frame mainte- nance and its subversion during translation of the genetic code. Biochimie 114:90 -96. http://dx....
Roughly half of the identified phage peptides in each sample mapped only to proteins predicted using genetic code 15. Figure 1 shows the genome maps of the target phages in each sample, with the locations of predicted and detected proteins using either code 11 or code 15 translation. Some of...
Genetic code Complementary sequence Peptide interaction Hydrophobic Lipophilic mRNA tRNA 1. Introduction The standard genetic code defines rules for the transcription of biological DNA and RNA information, and related protein synthesis, namely translation rules. It is often described as a translation table...
that evolutionary changes of the meaning of UAG and UAA codons in nuclear genomes can be decoupled and that the interpretation of the two codons by the cytoplasmic translation apparatus is mechanistically separable. The latter conclusion has interesting implications for possibilities of genetic code engin...
Global alterations in the genetic code are usually caused by changes in the translation machinery. Recoding is observed at specific mRNA locations and can be modulated by a variety of cis-elements and trans-factors. Diverse recoding phenomena include the incorporation of non-standard amino acids, ri...
PartI:ChemistryandGeneticsPartII:MaintenanceoftheGenomePartIII:ExpressionoftheGenomePartIV:RegulationPartV:Methods 3/22/05 PartIII:ExpressionoftheGenome Ch12:MechanismsofTranscriptionCh13:RNASplicingCh14:TranslationCh15:TheGeneticCode MolecularBiologyCourse CHAPTER15 TheGeneticCode CHAPTER15TheGeneticCode Topic1...
Here we provide a broad investigation of the portability of many different sets of genetic code expansion technologies fromE. colitoB. subtilis, and we use several of these systems to gain insights about protein translation and cell division inB. subtilis. This work builds substantially upon recent...
protein engineering can be divided into two groups: first, amino acids which are isostructural to cAAs and therefore recognized by the endogenous host cell machinery, and second, amino acids which are orthogonal to the host cell system because they do not participate in conventional translation. To...