Loss-of-function, by deletion or mutation, of genes that code for ribosomal proteins are known as ribosomopathies and are causally associated with various human diseases, most prominent of which is the Diamond-
The topographic specificity of the HOX code is maintained during differentiation, suggesting that they are an intrinsic property of MSC. Furthermore, specific HOX gene expression profiles of stem and progenitor cells from mesodermal tissues, the so called "biological fingerprint" can be used to ...
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If we have two copies of a particular gene type, that’s calledhomozygous. If we have one copy of one type, and a different copy of another type, that’s calledheterozygous. Figure 5.1: Homozygous and heterozygous inheritance Interestingly, many traits that are supposedly one-gene, ormonogenic...
The present invention relates to novel DNA sequences encoding insecticidal Cry1 C proteins derived from Bacillus thuringiensis, and their use in plants to control insect pests. Also included herein are plant cells or plants comprising such genes and methods of making or using them, as well as ...
SCGB 1A1 proteins were detected in distal lung bronchioles (A), uterine glands (B), and Fallopian tube (C). Inserts are sections incubated with pre-immune serum instead of primary antibody. Note that not all cells within each epithelial layer express SCGB 1A1. Full size image Analysis of ...
Long noncoding RNAs (lncRNAs) are functional bridges connecting the genome with phenotypes by interacting with DNA, mRNA, and proteins. Using publically available acute heat stress (AHS)-related RNA-seq data, we discovered novel lncRNAs and tested their
Moreover, RIP-Seq assays demonstrated that HSPA5 immunoprecipitates specific cellular mRNAs such as EGFR, NEAT1, LRP1 and TGFß1, which are important in the pathology of NAFLD. Finally, HSPA5 binding sites may be associated with splicing sites. We used the HOMER algorithm to search for ...
The EPX gene is activated during an immune response, releasing proteins and other components in the area of injury or inflammation that have a toxic effect on severely damaged cells or infecting pathogens. One of these proteins is called eosinophil peroxidase, that are extremely cytotoxic to b...
Uterine fibroids (UF), that can disrupt normal uterine function and cause significant physical and psychological health problems, are observed in nearly 70% of women of reproductive age. Although heritable genetics is a significant risk factor, specific