RHCE-D-CE hybrid genes can cause false-negative DNA typing of the Rh e antigen.Rhodiume antigenPolymerase Chain ReactionDNA铑聚合酶链反应BACKGROUND AND OBJECTIVES: DNA typing of the human Rh blood groups generally shows good agreement with serologically defined phenotypes. However, in the present ...
Innan H (2003b) A two-locus gene conversion model with selection and its application to the human RHCE and RHD genes. Proc Natl Acad Sci USA 100:8793–8798 Article PubMed CAS Google Scholar Innan H (2004) Theories for analyzing polymorphism data in duplicated genes. Genes Genet Syst 79...
The distributions of both TH and EYFP-IR immunofluorescence at E13.5 (Fig. 2A) appeared largely bimodal, with adrenal chro- mrCohabaflfnainsetstceafrlll.os1m7cslhuthosteweseruidnptgrhaiarnteintmhaelmglouawnnogerlriearaiccglthuivtsitrteeyrgetiodonCinAotfRhtTeheuwpgaprsaesprphleec(fiTtfirHcegt...
and c.1048G>C (p.D350H), were found.ConclusionFor the first time, a QMPSF-based method is reliable to individually quantify the exons of both RH genes, including hybrid D-CE genes in compound heterozygous samples and may help to investigate samples with unknown RHD and/or RHCE status....
F. SchunterMolecular DiagnosticsVox SanguinisHundhausen T, Petershofen EK, Doescher A, Bauerfeind U, Muller TH, Schunter F. RHCE-D-CE hybrid genes can cause false-negative DNA typing of the Rh e antigen. Vox Sang. 2002;83:268-72.
The genotypes can be matched based on the weighted clinical significance of a genotypic difference between donor and recipient, such that certain mismatches are more acceptable than others.doi:US7612193 B2Ghazala HashmiMichael SeulMarion E. ReidMichael PierceUS...
RHDBackground and Objectives The Rh blood group system is the most polymorphic human blood group system. Previous studies have investigated variants in the RHD and RHCE promoter. The relevance of these variants to the Chinese Han population is further clarified in this study. Materials and ...
RH genevariantThe discovery and characterization of the RH genes, i.e., RHD and RHCE, in the early 90s have been milestones in the field of blood group genetics. In addition to the single nucleotide variants (SNVs), which are commonly considered as the predominant molecular actors resulting...
RHCERHDSchizophreniaSexual orientationMedea factors or genes are maternal-effects mechanisms, found in many species, in which the mother's body selectively kills embryos of a certain genotype.Humans have a similar genetic mechanism, the gene RHD which produces Rh-factor involved in blood type....
Local sequence determinants of two in-frame triplet deletion/duplication hotspots in the RHD/RHCE genesdoi:10.1186/1479-7364-6-8Jian-MinChenDavidNCooperClaudeFérecSpringerHuman Genomics