KRT19 and KRT5 proteins were up-regulated in A/S, while KRT2.13 protein was down-regulated. KRT2.13, as a hair-like gene, was supposed to be inactive in hair follicles54. Dowling-Degos disease, characterized
There are correlations between the location of mutations in the FA complex proteins and the residual activity of theligase. Thus, most mutations in the FA complex lead to truncated proteins and are found in the periphery of the FA core complex. Overall, the ligase has a certain residual activ...
and then transferred into a 50 mL centrifuge tube. Proteins were extracted as described by Komatsu51. The proteins were air-dried and re-suspended in lysis buffer (8 M urea, 5% CHAPS, 2 M thiourea and 2 mM tributylphosphine). The suspension was centrifuged at...
The first eukaryotic CRPs characterized in detail were isolated from the rat cytoribosome [3]. Individual proteins were separated by two-dimensional gel electrophoresis and named from their origin in the small (S) or large (L) subunit and their relative electrophoretic migration positions, for examp...
The genomes of worldwide poultry breeds divergently selected for performance and other phenotypic traits may also be affected by, and formed due to, past and current admixture events. Adaptation to diverse environments, including acclimation to harsh cli
Grain weight (GW) is a key component of sunflower yield and quality, but may be limited by maternal tissues. Cell growth is influenced by expansin proteins that loosen the plant cell wall. This study aimed to identify spatio-temporal expression of EXPN g
In the nucleus, some RNA-binding proteins (RBP) often function as AS regulators in a particular way in the disease course [13, 14]. Functional disruptions in RBPs may be a major cause or consequence of a disease [15, 16]. CUGBP Elav-like family (CELF) and muscleblind-like (MBNL) ...
from both OR and HB methods. Second, using genes identified by the above prioritizing methods as seeds, we apply the Random Walk with Restart algorithm (RWR) to propagate the influences of these seeds to other proteins in protein-protein interaction (PPI) networks. As such, many proteins ...
(RLK) or receptor-like proteins (RLP) [11]. To facilitate infection, pathogens can secrete effectors that can be recognized by resistant (R) genes and then trigger ETI [12]. Apart from several RLPs, most identified R genes belong to the Nucleotide Binding Site-Leucine-Rich Repeat (NBS-...
A protein–protein interaction (PPI) network of the identified DEGs with an interaction score > 0.4 was constructed by the Search Tool for the Retrieval of Interacting Genes/Proteins (STRING). The DEGs and their related genes were presented with at least 2 interactions. Subsequently, the fun...