pfam14771; Supplementary Fig.1). However, the C-terminal part of the protein contains a novel motif that is specific to spiralianlophotrochingenes and is strongly conserved. This protein
These arbitrary settings work well in these specific studies, but may have limited utility in other experimental systems. Therefore the question of how to deal with the distal effects of mutations remains challenging. We considered an integrative impact of insertions on gene essentiality, i.e. ...
The Childhood Asthma Management Program (CAMP) study was also used to replicate a specific gene-gene (VDR- IL10) interaction models. The CAPPS and SAGE studies have been described elsewhere [26]. Briefly, the CAPPS study was initiated in 1995 to assess the effectiveness of a multifaceted ...
This is created by the function DBBuilder.totalWordCounts that essentially uses the same algorithm as the main gene word search, but instead of for specific genes, it adds the annotations for all of the genes in the database and just doesn't store some of the superfluous information. It ta...
$ genomepy providers GENCODE Ensembl UCSC NCBI Local URL List available genomes You can constrain the genome list by using the-p/--provideroption to search only a specific provider. Additionally, you can get the absolute--sizeof each genome (this option slows down the search). ...
In the genome ofP. infestans, 563 effector genes with the RxLR motif have been identified (Haas et al.2009). For 15 of them, the respective potatoRpigenes have been identified (Table4). According to the gene-for-gene concept, specific pathogen effectors activate corresponding host plant R pr...
To test whether the interacting TFs ASCL1, NKX2-1, and PROX1 work together to direct SCLC-A-specific gene expression needed to maintain cell growth, we assayed cell viability after siRNA knockdown of these TFs individually or in combination. Confirming previous findings, a decrease of ASCL1 ...
Any gene set with a high OCP contains condition-specific biomarkers. Genes with a high OCP and a high FCP (e.g. candidate genes) might also have a higher probability of encoding biological processes relevant to the condition being classified. What is the reason for variation in FCP in genera...
Third, cancer genomics will benefit by producing ‘functional encyclopedia’ and ‘biochemical pathways atlas’ for organ-specific cancers including cancer subtypes. Finally, basic research in molecular biology has been based on the premise that ‘one doesn’t know what’s abnormal unless one finds ...
However, analysis of the Duplicate-Free Microarray Atlas suggests that this pattern of tissue-specific expression is driven primarily by duplicated genes (see Figure 6B). Using the Six-Tissue RNA-Seq Atlas, we found lower tissue-specificity for high-scoring neighborhoods (see Figure 6C) while the...