MicroRNAs play a crucial role in regulating the immune responses induced by ischemia/reperfusion injury. Through their ability to modulate gene expression, microRNAs adjust immune responses by targeting specific genes and signaling pathways. This review
Results & discussion Equipped with next-generation sequencing techniques, international collaboration programs on cancer genomics have identified numerous mutations, gene fusions, microsatellite variations, copy number variations, and epigenetics changes that promote the transformation of normal cells into tumors....
Agencourt Bioscience Corporation, The Broad Institute of MIT and Harvard and the Washington University Genome Sequencing Center were supported by grants and contracts from the National Human Genome Research Insititute (NHGRI). T.C. Kaufman acknowledges support from the Indian Genomics Initiative. Author ...
BMC Genomics volume 25, Article number: 293 (2024) Cite this article 1303 Accesses 1 Citations Metrics details Abstract Background Alternative splicing (AS) is a principal mode of genetic regulation and one of the most widely used mechanisms to generate structurally and functionally distinct mRNA ...
Functional Genomics Microbial Biooceanography Background Within the last few decades, targeted amplicon sequencing and shotgun sequencing have been used to detect the composition and potential functions of microbial communities. 16S rRNA gene sequencing is the most widely used amplicon sequencing method. ...
(utilising TruSeq mRNA kits by Illumina, located in San Diego, CA, USA) and were multiplexed at the National Genomics Infrastructure Sweden. The cBot system was utilised for clustering, and sequencing was carried out using the NovaSeq6000 system (operating with NovaSeq Control Software 1.6.0 and...
The main genetic variants that are present in both the virus and host genomes were particularly focused on the ACE2 and TMPRSS2 genes, and their impact on the patients' susceptibility to the virus infection and severity of the disease. Finally, the interaction of the virus and host non-...
quality of mapping was assessed with the SAMStat package [66], as well as Qualimap [67]. Sequence alignment files were indexed using SAMtools [68], and mapped reads were visually inspected by applying the Integrative Genomics Viewer (IGV; [69]. All further computational and graphical analyses ...
Functional genomics reveal that the serine synthesis pathway is essential in breast cancer Nature, 476 (2011), pp. 346-350 CrossrefView in ScopusGoogle Scholar Riaz et al., 2019 S.K. Riaz, Y. Ke, F. Wang, M.A. Kayani, M.F.A. Malik Influence of SHH/GLI1 axis on EMT mediated mi...
Conclusions The extensive atlas of GWAS, eQTL, fine-mapping, and transcriptome-wide association studies aid in the suggestion of potentially functional variants and genes in cattle agronomic traits and will be an invaluable source for genomics and breeding in beef cattle.Introduction...