Activation of nuclear transcription factors and protective genes in the vascular adaptive response to chronic liver hypoxiadoi:10.1080/03610926.2013.777741Primary 62G08Secondary 62G05Li et al. (2007) developed an estimation method for quantile functions in a reproducing kernel Hilbert space for ...
We used asteroid-inducible system to show that the transcription factor-type response regulator ARR1 directs transcriptional activation of the ARR6 gene, which responds to cytokinins without de novo protein synthesis. This fact, together with characteristics of ARR1-over-expressing plants and arr1 ...
RAV transcription factors are essential for disease resistance against cassava bacterial blight via activation of melatonin biosynthesis genes 来自 dx.doi.org 喜欢 0 阅读量: 343 作者:Y Wei,Y Chang,H Zeng,G Liu,C He,H Shi 摘要: With one AP2 domain and one B3 domain, 7 MeRAVs in apetala...
Grainyhead-like 1 (GRHL1) is a transcription factor involved in embryonic development. However, little is known about the biological functions of GRHL1 in cancer. In this study, we found that GRHL1 was upregulated in non-small cell lung cancer (NSCLC) and correlated with poor survival of p...
and higher-order clusters known as transcription factories32,33,34,35, and active genes tend to colocalize within transcriptionally active subcompartments27,36. On the other hand, there are cases in mammalian cells where significant unfolding of genes occurs after strong transcriptional activation37,...
Our next effort was to identify downstream responses associated with p38δ activation. C/EBP and AP1 transcription factors are known to be important in regulation of keratinocyte differentiation (13, 18, 19, 29–36). We therefore examined the effects of OA treatment on AP1 and C/EBP factor ex...
Activation of signal transducer and activator of transcription 3 protects cardiomyocytes from hypoxia/reoxygenation-induced oxidative stress through the upregulation of manganese superoxide dismutase. Circulation. 2001;104:979–81. Article CAS PubMed Google Scholar Yoshimura A, Naka T, Kubo M. SOCS ...
Geriatric people are prone to suffer from multiple chronic diseases, which can directly or indirectly affect renal function. Through bioinformatics analysis, this study aimed to identify key genes and pathways associated with renal insufficiency in patie
This binding activates small G proteins, such as Rac and Rho, which are implicated in the establishment of cell polarity and cell migration [23]. In addition, the activation of these pathways may inhibit the canonical Wnt pathway [24,25]. The WNT-Ca2+ pathway regulates calcium release from ...
transcription factor (TF) binding sites and are generally located nearby genes already implicated in craniofacial abnormalities. However, these enrichments are driven by a relatively small fraction of all identified craniofacial enhancers, and it is unclear exactly which genes these enhancers regulate. ...