It is shown that these equivalence classes are related with the amino acid properties that are important for the formation of the protein structure. The algorithm presented in this study works best for bit-patterns, which are frequently encountered in bit-vector representations.Witold R. Rudnicki...
Deep learning methods have revolutionized protein structure prediction and design but are currently limited to protein-only systems. We describe RoseTTAFold All-Atom (RFAA) which combines a residue-based representation of amino acids and DNA bases with an atomic representation of all other groups to...
amino acid properties Amino acid property Hydrophobicity index Signal sequence helical potential Membrane-buried preference parameters Conformational parameter of inner helix Conformational parameter of beta-structure Conformational parameter of beta-turn Average flexibility indices Information value for accessibilit...
16The most frequent missense consists of amino-acid substitution (glutamine, leucine, or tryptophan for arginine) at position 482.17Lamins belong to the intermediate filament family of proteins that compose the nuclear lamina, a polymeric structure intercalated between chromatin and the inner nuclear ...
A cascading system of hierarchical, artificial neural networks (named PRED-CLASS) is presented for the generalized classification of proteins into four distinct classes-transmembrane, fibrous, globular, and mixed-from information solely encoded in their amino acid sequences. The architecture of the indiv...
On the structure of free baxter algebras A Baxter algebra is a commutative algebra A together with a linear operator P such that P( ab) + P( a) P( b) = P( aP( b)) + P( bP( a)) holds for any pair a... P Cartier - 《Advances in Mathematics》 被引量: 363发表: 1972年 ...
In semiconductor particles of nanometer size, a gradual transition from solid-state to molecular structure occurs as the particle size decreases. Consequen... H Weller - 《Angewandte Chemie International Edition in English》 被引量: 3164发表: 1993年 Kinetics of II-VI and III-V Colloidal Semicond...
However, the relationship between the structure and the functions of the variant receptors have not been studied previously. We herein report a new point mutation found in a Japanese family, i.e. a cyto- sine to adenine base change, which causes an amino acid substitution from phenyl- alanine...
In previous papers, a method of protein tertiary structure recognition was described based on the construction of an associative memory Hamiltonian, which encoded the amino acid sequence and the C伪 co-ordinates of a set of database proteins. Using molecular dynamics with simulated annealing, the ...
The beta subunit of the heterotrimeric G proteins that transduce signals across the plasma membrane is made up of an amino-terminal alpha-helical segment f... I Garcia-Higuera,C Gaitatzes,TF Smith,... - 《Journal of Biological Chemistry》 被引量: 181发表: 1998年 The Structure of Aip1p,...