PROBLEM TO BE SOLVED: To provide a method for producing, in a high yield, a 3,3,3-trifluoro-2-hydroxy-2-trifluoromethylpropanoic acid ester which is expressed by the general formula: (CF)C(OH)COOR, in a high yield and is free from the problem of waste material treatment.小金 敬介...
Unless clearly contraindicated by the context each compound name includes the free acid or free base form of the compound as well as all pharmaceutically acceptable salts of the compound.The term “Formula (I)” encompasses all compounds that satisfy Formula (I), including any enantiomers, race...
A method for the asymmetrical synthesis of S-acylated derivatives of 2-mercaptomethyl 3-phenyl propanoic acid of formula (I) is disclosed. The method comprises the steps of (a) preparing diol (VI) by reducing a malonic ester (V) in the p... Danvy,M Denis,D Thierry,... - EP 被引量...
In certain embodiments, the compound inhibiting Aβ peptide polymerization is selected from the group consisting of formula I-IV: wherein, independently for each occurrence, R1, R2, R3, R4, R5, R6, R7, R8, R9, and R10 are hydrogen, halo, azido, alkyl, haloalkyl, perhaloalkyl, fluoro...
Typical compounds represented by structures of Formula III include alkylphenols such as nonylphenol, or dinonylphenol, octylphenol, 3(2-hydroxyphenyl)propionic acid, 3(2-hydroxyphenyl)propanol, 2-methoxy-4-allylphenol, 2-allylphenol and bisphenols including 2,2-bis(4-hydroxyphenyl)propane, 2,2-bis(...