-genelist To run vegas2 on specific list of genes. -top It tell vegas2 to perform top percentage test where it consider specified percentage of top SNPs -bestsnp It tell vegas2 to perform best SNP test. -sex This option is provided for X-chromosome analysis. It tells vegas2 to consider...
Gene-based test for 139 candidate genes using the single nucleotide polymorphisms selected by physical location.Dounya, SchoormansJingmei, LiHatef, DarabiYvonne, BrandbergMirjam, A. G. SprangersMikael, ErikssonKoos, H. ZwindermanPer, Hall
cd geneiase bin/geneiase -t static -i test/static.test.input.tab -b 100 bin/geneiase -t icd -i test/icd.test.input.tab -b 100 Optionally add geneiase to your shell PATH By adding the 'geneiase/bin' directory to your shell PATH you can execute the program without needing to enteri...
Generalized score test and likelihood ratio test statistics are derived to test for the association between bivariate survival traits and the genetic region. Extensive simulation studies are conducted to evaluate the type-I error control and power performance of the proposed approach, with comparisons ...
We propose BIGKnock (BIobank-scale Gene-based association test via Knockoffs), a computationally efficient gene-based testing approach for biobank-scale data, that leverages long-range chromatin interaction data, and performs conditional genome-wide test
are drawn in gray. Associations withp > 0.1 in both analyses are not shown.dFor significant gene-biomarker associations in either analysis, we show if the variant effect types and the test-types (gbvc or kernel-based) which gave the smallestpvalues were consistent between the two ...
“unexpressed” genes with RPKM < 1. We held out genes on one chromosome at a time as a test set and used genes on all other chromosomes as a training set. We calculated the median expression for each ChromGene annotation for genes in the training set and used this as a predictor...
The CRISPR/Cas9 system is a powerful method of editing genes by randomly introducing errors into the target sites. Here, we describe a CRISPR-based test for gene essentiality (CRISPR-E test) that allows the identification of essential genes. Specifically
Thus, results from gene level association test can be more readily integrated with downstream functional and pathogenic investigation, whereas many existing methods for multiple trait association tests only focus on testing a single common variant rather than a gene. We propose a statistical method by...
The cone penetrometer test is widely used for in situ site investigations and for establishing direct penetrometer-to-foundation or -anchor design correlat... Y Wang,MS Hossain,Y Hu - 《International Journal of Physical Modelling in Geotechnics》 被引量: 0发表: 2022年 ...