Researchers funded by the Canadian Cancer Society have discovered eight similar genes that, when mutated, appear to be responsible for medulloblastoma - the most common of childhood brain cancers. The findings are published today in the online edition of the journalNature Genetics. "This discovery is...
MELBOURNE, June 21 (Xinhua) -- A study published on Wednesday has brought Australian researchers a step closer to understanding gene mutations that can cause breast cancer. Scientists from the University of Melbourne and Peter MacCallum Cancer Centre have for the first time accurately established the...
says Lui. While a lot of discovery is still needed to find more mutations in the MAPK pathway and the drugs that target them, Lui says they are among the most logical treatment targets for this tough-to-treat cancer.
Therefore, gene mutations are typically recessive and thus unable to generate dominant phenotypes. The argument, that all hypothetically carcinogenic gene mutations are exceptional dominants, is hard to rec...
However, cure cancer would need a breakthrough innovation. Recent years, we saw dramatic progress in cell and gene therapy, with new approaches repairing or overriding the DNA mutations that cause diseases. With cell and gene therapy, the diseased cells with tumor could be replaced with he...
Novel and more effective way of testing which gene mutations cause cancertext editorEmerging Infectious Diseases
The CRISPR system is a revolutionary genome editing tool that has the potential to revolutionize the field of cancer research and therapy. The ability to precisely target and edit specific genetic mutations that drive the growth and spread of tumors has
assaying of fermentation broth/agar for products and scoring for improved strains. It must be emphasized that the action of the mutagenic agent on DNA not only can cause genetic alteration but can also induce cell death, owing to irreversible damage to the DNA or formation oflethal mutations. ...
“In most cases, we don’t understand why the mutations that ultimately lead to cancer occur,” Curtin says. But some populations are prone to them. He notes that EGFR mutations cause about 10 to 15% of lung cancers in the U.S. and up to 50% in eastern Asia. Patients with EGFR-mut...
Paclitaxel Resistance in Non–Small-Cell Lung Cancer Associated With Beta-Tubulin Gene Mutations The mechanisms that cause chemoresistance in non-small-cell lung cancer (NSCLC) patients have yet to be clearly elucidated. Paclitaxel is a tubulin-disrupt......