Prickett M, Jain M. Gene therapy in cystic fibrosis. Transl Res. 2013;161(4):255-64.Prickett M, Jain M. Gene therapy in cystic fibrosis. Transl Res 2013;161:255-64.Prickett M, Jain M (2013) Gene therapy in cystic fibrosis. Transl Res 161(4):255–264...
“While this is obviously not a home run, I do think the results are impressive. I’m pleased that gene therapy has been shown to safely deliver statistically significant treatment effects,” saysOli Rayner, who has cystic fibrosis and works as an advocate for those who have the disease ...
Cystic fibrosis (CF) is the most common life-limiting fatal genetic disorder, affecting approximately 90,000 individuals worldwide [1]. It is an autosomal recessive disorder that requires mutations in the CF gene in both genetic alleles [2]. The CF gene encodes for a protein the cystic fibros...
Cystic fibrosis (CF) is a common genetic disorder in the Caucasian population. The gene was identifi
The discovery of the Cystic fibrosis (CF) gene in 1989 has paved the way for incredible progress in treating the disease such that the mean survival age of individuals living with CF is now ~58 years in Canada. Recent developments in gene targeting tools and new cell and animal models ha...
Essential genome of Pseudomonas aeruginosa in cystic fibrosis sputum. Proc. Natl Acad. Sci. USA 112, 4110–4115 (2015). Article CAS PubMed PubMed Central Google Scholar Le Breton, Y. et al. Essential genes in the core genome of the human pathogen Streptococcus pyogenes. Sci. Rep. 5, ...
Update on gene modifiers in cystic fibrosis. PURPOSE OF REVIEW: (CF) is a common, life-limiting monogenic disease, which typically manifests as progressive , exocrine pancreatic dysfunction, and recur... JM Collaco,GR Cutting - 《Current Opinion in Pulmonary Medicine》 被引量: 177发表: 2008年...
Gene therapy for cystic fibrosisSOTOS SYNDROMEEPILEPSYNo Abstract available for this article.doi:10.1038/nm0395-182aDodgeJ.A.Nat MedNature Medicine
Cystic fibrosis is caused by a gene called CFTR. A. 相关知识点: 试题来源: 解析 B [概括大意] 见第三段第一句,“Cystic fibrosis is caused by defects in a gene called CFTR.”囊性纤维变性是由一种叫做CFTR的基因的缺陷所造成的。反馈 收藏 ...
Cystic fibrosis is an autosomal recessive disease caused by mutations of the CFTR protein, a member of the ATP-binding cassette superfamily of transmembrane proteins. CFTR can act as a cAMP-activated chloride channel and as a regulator of other ion channels in exocrine glands and other ductular ...