1911年,源自德语“Gen”,该术语于1905年被丹麦科学家威廉·路德维克·约翰森(1857-1927)创造。它来自于希腊语“genea”即“生成功能、种族”(源自 PROTO INDUROPEAN 词缀“*gene-”,意为“生育、产生”)。德国植物学家 De Vries 最初将其称为“pangenes”。“Gene pool”是在1946年首次发现。
good evidence that (i) the proposed candidate gene is biologically relevant to the trait of interest, (ii) the variants of the candidate gene influence the overall function of the gene, and (iii) the polymorphisms of the selected candidate gene are frequent enough in the population to allow ...
(Gardneret al., 2003). This network identifies similarly behaving genes from the perspective of abundance and infers a common function that can then be hypothesized to work on the same biological process. A good example of a co-expression network are genes that are coregulated during diauxic ...
1a)59,70. Clustering of single-cell expression profiles from wild-type and mutant embryos showed good concordance with bulk RNA-seq data (Extended Data Fig. 3a) and identified 15 clusters representing different cell identities in the embryo (Fig. 2a,b and Extended Data Fig. 3c). We ...
Galloway and Goodenough (1985) proposed a model in which the mt locus (linkage group VI) is a complex region containing several genes involved in the control of both gametic differentiation and cp inheritance. The mt + locus contains: the sfu locus necessary for sexual fusion between gametes;...
As an information environment, the World Wide Web is informatically representative of all that is good and bad about the human need to both absorb and transmit knowledge. The 'open' nature of the Web makes instantly available, to anyone who can "log-on", a boundless digital library of ...
Understanding how microbial pathogens adapt to treatments, humans and clinical environments is key to infer mechanisms of virulence, transmission and drug resistance. This may help improve therapies and diagnostics for infections with a poor prognosis, s
These differential genes have good application prospects for the diagnosis and treatment of COVID-19 and provide new perspectives for the discovery of potential biomarkers and drug targets of COVID-19. Methods Data Sources To analyse the biological mechanisms and potential therapeutic targets of ion ...
Gametes of Chlamydomonas reinhardi become activated for cell fusion as the consequence of sexual adhesion between membranes of mating-type plus and minus f... UW Goodenough,Patricia A. Detmers and Carol Hwang - 《Journal of Cell Biology》 被引量: 144发表: 1982年 ...
become a fundamentalist religious zealot or even become institutionalised. Generally, these instances are rare because our body is very good at correcting mistakes, but it does happen. If nothing else, this serves to remind us that our biology makes us who we are, we should take nothing for...