he went to graduate school at Caltech and then worked at the University of Utah before shifting to the University of Chicago, where he spent the rest of his illustrious career. Parker’s most important scientific works are
作者: H Golub 摘要: It is a great honor to be here and to speak in this forum. Today has been a wonderful day here in Groningen and I have just been enormously stimulated. Not only is it a great honor to speak in a series named after Johann Bernoulli, but also because some of my...
Golub, E.S. Lander, J.P. Mesirov Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles Proc. Natl. Acad. Sci. U.S.A., 102 (2005), pp. 15545-15550 CrossrefView in ScopusGoogle Scholar Szklarczyk et al., 2015 D. Szklarczyk, A. ...
Different analytical tools have been proposed for analysing microarray data (Eisen et al, 1998; Golub et al, 1999; Kalocsai and Shams, 2001; Tamayo et al, 1999; Toronen et al, 1999; Bittner et al, 2000). Our goal was to identify the gene expression profiles of cells treated with the ...
Obtaining physiological insights from microarray experiments requires computational techniques that relate gene expression data to functional information. Traditionally, this has been done in two consecutive steps. The first step identifies important gen
Golub, E.S. Lander, J.P. Mesirov Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles Proc. Natl. Acad. Sci. USA, 102 (2005), pp. 15545-15550 CrossrefView in ScopusGoogle Scholar Sun et al., 2017 M. Sun, W. Bell, K.D. LaClair...
Krivtsov AV, Twomey D, Feng Z, Stubbs MC, Wang Y, Faber J, Levine JE, Wang J, Hahn WC, Gilliland DG, Golub TR, Armstrong SA. Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9. Nature. 2006;442:818–22. https://doi.org/10.1038/nature04980. Article...
[39,40]. In 1999, Golub et al. introduced gene expression profiling as an approach to validate the outcome of clinical diagnosis [21]. Thirty-eight acute leukemia cases from diagnosed patients (27 ALL, 11AML) were acquired in that study. Thirty-eight total RNA samples extracted from acute ...
Stress is a recognized risk factor for mood and anxiety disorders that occur more often in women than men. Prefrontal brain regions mediate stress coping, cognitive control, and emotion. Here, we investigate sex differences and stress effects on prefront
J Clin Invest 2003;112:83-90 Mikhail N, Golub MS, Tuck ML. Obesity and hypertension. Prog Cardivasc Dis 1999;42:39-58 Miller SA, Dykes DD, Polesky HF. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 1988;16:1215 Ortiz MA, De Prado A...