Explore the concept of gene flow. Learn gene flow definition and meaning, and discover what produces gene flow. Identify gene flow examples in plants, animals, and humans. Related to this Question How can migration and gene flow affect a population?
Explore the concept of gene flow. Learn gene flow definition and meaning, and discover what produces gene flow. Identify gene flow examples in plants, animals, and humans. Related to this Question What is gene flow? What does gene flow depend on?
It is known that there was gene flow from Neanderthals to modern humans around 50,000 years ago; now, analysis of a Neanderthal genome from the Altai Mountains in Siberia reveals evidence of gene flow 100,000 years ago in the other direction—from early
MODERNapplyAlthough it is well known that the ancestors of modern humans and Neanderthals admixed,the effects of gene flow on the Neanderthal genome are not well understood.We develop methods to estimate the amount of human-introgressed sequences in Neanderthals and apply it to whole-genome...
Extreme independent variation in the expression of pairs of HLA-associated transcripts (HLA-B/C, HLA-A/F and HLA-DRB1/DRB5) in macrophages was associated with HLA genotype. Correlation analysis indicated the downstream impacts of variation in the immediate early response to LPS. For example, ...
The therapeutic potential of each of these has been explored in cardiovascular disease models and examples of these are given in the subsequent text. In addition to the generic limitations of non-viral vectors, oligonucleotides are also constrained by the problems of short biological half-life and ...
Gene drives are genetic modifications designed to propagate in a population with high efficiency. Current gene drive strategies rely on sexual reproduction and are thought to be restricted to sexual organisms. Here, we report on a gene drive system that
in the absence of TCRβexpression (Ehlichet al., 1993; Mombaertset al., 1992a). Finally, rearrangement on both alleles of normally allelically excluded loci has also been observed (Balomenoset al., 1995). These examples illustrate the multiplicity of situations observed with respect to re...
The choice of these two genes had, as a parameter, the fact that the CNRIP1 and PPP3R1 genes are related to cancer in humans. To quantitatively investigate the expression of the candidate genes of the DFNA58 locus by analyzing their mRNA (Cnrip1a-NM_001003607.2, Cnrip1b-NM_001327770.1...
A long-standing problem in regulatory genomics is that of predicting gene expression purely from DNA sequence. With a novel transformer architecture, we have made a significant improvement by greatly expanding the receptive field and increasing the information flow between distal elements. In this way...