If a study in a specific developing organ, it reports expression of several genes, or of a single gene if it has high intrinsic interest It reports the results of an in situ screen The study must be detailed and with high quality data, such that it provides a definitive analysis of the...
In any gene expression study, selecting a valid normalization or endogenous control to correct for differences in RNA sampling is critical to avoid misinterpretation of results. TaqMan Endogenous Controls consist of the most commonly used housekeeping genes in huma...
The CommonMind Consortium sequenced RNA from dorsolateral prefrontal cortex of subjects with schizophrenia (N = 258) and control subjects (N = 279), creating a resource of gene expression and its genetic regulation. Using this resource, they found that
AlthoughC. pilosulais a traditional Chinese medicine, insufficient researches have been conducted on the internal reference genes for gene expression normalization in biosynthesis of its main components. As a result, the synthesis mechanism is not clear by now. Fortunately, Gao, J. P.et al. initia...
Order journal Guide for authors About the journal Gene Reportsis a companion title toGeneand a member of theGene Family.Gene Reportspublishes papers that focus on theregulation, expression, functionandevolutionofgenesin all biological contexts, including all prokaryotic and eukaryotic organisms, as well...
Sensitive high-throughput RNA-seq methodology captures variation in gene expression, which precedes other robust and subtle dimorphic phenotypes. Fruit flies have been used to study sex differences in the brain via RNA-seq, including responses to traumatic brain injury, cocaine, and developmental alcoho...
Survival analysis on gene expression (RNA-seq) in bladder cancer TCGA data - hamidghaedi/RNA-seq-survival-analysis
Figure 1.Flowchart of the whole study. Abbreviations: ccRCC, clear-cell renal cell carcinoma; DEGs, differentially expressed genes. The selection of prognosis-related genes and signature development phases was carried out using The Cancer Genome Atlas (TCGA) dataset. Level 3 RNAseq expression data ...
Gene expression analysis techniques that use this approach have been limited by their ability to study only a few transcripts per experiment. Other techniques include dot blotting, ribonuclease protection assays (RPAs), serial analysis of gene expression (SAGE), and differential or subtractive ...
Long non-coding RNAs (lncRNAs) are diverse transcription products emanating from thousands of loci in mammalian genomes. Cis-acting lncRNAs, which constitute a substantial fraction of lncRNAs with an attributed function, regulate gene expression in a man