Database on Signal Transduction Pathways Regulatory Networks: General Properties and Peculiarities Variety of Databases on Protein Interactions and Signaling Networks TRANSPATH® – A Database on Signal Transduction Pathways Application of the Databases for Causal Interpretation of Gene Expression DataAnalysis...
M. et al. Local regulation of gene expression by lncRNA promoters, transcription and splicing. Nature 539, 452–455 (2016). This study demonstrates that promoters of some lncRNAs, but also of some mRNAs, affect the expression of neighbouring genes, emphasizing that studies of the functions of...
Therefore, regulation of gene expression can happen at any of these steps. In eukaryotes, gene regulation occurs at any of the following steps: Transcriptional level i.e. during the formation of the primary transcript. Processing level i.e. at the stage of splicing. During transport of mRNA ...
第十六章 基因表达调控 （RegulationofGeneExpression）本章主要内容 基因表达调控概念与转录调节的基本要素原核生物基因转录调控真核生物基因表达调控 第一节 基因表达调控概念 与转录调节基本要素 一、基因表达的概念二、基因表达的特点三、基因表达的方式四、基因表达调控的生物学意义五、基因转录激活调节的...
The developmental Genotype-Tissue Expression (dGTEx) projects will catalogue and integrate gene expression, regulation and genetics data across 120 human donors from birth to adulthood with developmentally matched non-human primates, including 126 rhesus macaques and 72 common marmosets. ...
基因表达调控regulationofgeneexpression 蛋白质的合成 •合成体系：氨基酸、mRNA、tRNA、核糖体、某些酶与蛋白质因子、ATP、GTP、Mg •mRNA编码区的三个相邻核苷酸组成密码子•tRNA起接合器作用，核糖体是合成场所和 装配机•核糖体循环：起始、肽链延长和终止•翻译后加工：折叠、共价修饰、水解和亚 单位的...
The regulation of gene expression at the translational level not only allows for rapid changes in specific protein levels but also provides an opportunity to alter codon specificity. For the incorporation of selenocysteine (Sec) into protein, the UGA codon is transformed from one that signals transla...
Composite response elements mediate hormonal and developmental regulation of milk protein gene expression. Our laboratory has been studying the mechanisms by which hormones regulate the expression of differentiated function in the normal mammary gland and how th... JM Rosen,C Zahnow,A Kazansky,......
Global Regulation of Gene Expression by ArlRS, a Two-Component Signal Transduction Regulatory System of Staphylococcus aureus. Global regulation of gene expression by ArlRS, a two-component signal transduction regulatory system of Staphylococcus aureus. Liang X,Zheng L,Landwehr C,... X Liang,L ...
一、基因表达的概念基因表达（geneexpression）就是指在一定调节因素的作用下，DNA分子上特定的基因被激活并转录生成特定的RNA，或由此引起特异性蛋白质合成的过程。第十四章基因表达调控RegulationofGeneExpression 人类基因组DNA中约含5万个基因，但在某一特定时期，只有少数的基因处于转录激活状态，其余大多数基因则处于...