Biological processes depend on the differential expression of genes over time, but methods to make physical recordings of these processes are limited. Here we report a molecular system for making time-ordered recordings of transcriptional events into living genomes. We do this through engineered RNA ...
A central goal of this research is to predict the influence of genetic variants on cell-type-specific gene expression, in order to inform fine-mapping of the many thousands of noncoding associations with phenotypes of interest from genome-wide association studies (GWAS). Computational models that ...
genes down-regulated in tumors, the other 10% being upregulated. The profile shown is sorted by the geometric mean of the expression levels in the two tumor cell lines (right-hand column) in order to show the color differences most clearly. The key is located at the bottom of the figure...
Gene expression or messenger RNA (mRNA) analysis is the most commonly-used application for qPCR. Researchers reverse transcribe RNA, then use the cDNA produced as a template in qPCR reactions to detect and quantitate gene expression products TOP What is gene...
In order to have a graphical representation of the gene expression levels and their significance, we analyzed our results using volcano plots (Figure3). Figure 3 Microarrays volcano plots. Distribution of sequence expression between normal and normal injected with LPS, 3-, 7- and 14-dpe regenerat...
The fast growing field of molecular imaging has achieved major advances in imaging gene expression, an important element of gene therapy. Gene expression i
analysis of gene expression data [9–13] in order to extract associations and relationships among subsets of genes of the form: {[+]gene A→[+]gene B, [+]geneC}, meaning that when gene A is over-expressed it is also very likely to observe an over-expression of gene B and gene C...
The goal of GeneSwitches is to discover the order of gene-expression and functional events during cell state transitions at a single-cell resolution. It works on any single-cell trajectory or pseudo-time ordering of cells to discover the genes that act as on/off switches between cell states ...
In order to evaluate their relationship, the clinical findings fo... Dr.,RÉGis,Bataille,... - 《Cancer》 被引量: 608发表: 1981年 Gene expression profiling for molecular classification of multiple myeloma in newly diagnosed patients To identify molecularly defined subgroups in multiple myeloma, ...
2.5. Gene expression analysis In order to validate the stably expressed oil palm reference genes for RT-qPCR normalization, gene expression stability of β-actin (ACT), cyclophilin (CYP) and tubulin (TUB) were studied across three sets of oil palm tissues in various developmental stages. The fi...