Define gene expression. gene expression synonyms, gene expression pronunciation, gene expression translation, English dictionary definition of gene expression. Noun 1. gene expression - conversion of the information encoded in a gene first into messenger
High-throughput differential gene expression profiling, a transcriptomic approach, is a strategy that measures the activity/expression of thousands of genes at once, creating a comprehensive depiction of cellular function. From: Post-Genomic Cardiology (Second Edition), 2014 ...
DNA can determine where and when genes are expressed, but the full set of sequence determinants that control gene expression is unknown. Here, we measured the transcriptional activity of DNA sequences that represent an ~100 times larger sequence space than the human genome using massively parallel...
The definition of a perfect gene therapy vector is when the vector is capable of delivering a therapeutic gene and directing long-term expression of the gene in the target cells with high reliability and efficiency. Adenovirus, adeno-associated virus (AAV), lentivirus, murine retro-virus, and ...
Fig. 8: PHF3 regulates neuronal gene expression and neuronal differentiation of mouse embryonic stem cells (mESCs). aGO analysis of genes upregulated in PHF3 KO HEK293T cells according to RNA-seq shows enrichment of genes involved in neurogenesis. GSEA Biological processes tool was used.bTissueEn...
Vector analysis is a flexible, easy-to-use technique to compare gene expression patterns in different experimental backgrounds. It compares favorably with the classical Venn diagram approach and can be implemented manually using spreadsheets, such as Excel, or automatically by using the supplied software...
Clustering is crucial for gene expression data analysis. As an unsupervised exploratory procedure its results can help researchers to gain insights and formulate new hypothesis about biological data from microarrays. Given different settings of microarra
The coordinated transcriptional regulation of activated T-cells is based on a complex dynamic behavior of signaling networks. Given an external stimulus, T-cell gene expression is characterized by impulse and sustained patterns over the course. Here, we
Molecular signatures are often used to model patients' clinically relevant information (e.g., prognosis, survival time, etc) as a function of the gene expression data, but instead of using individual genes as predictors, the predictors are the signature components or "metagenes". In spite of ...
In both positive and negative control, a small signal molecule, the inducer, typically binds to the regulatory protein and induces gene expression. In the standard model of positive regulation, an inactive activator protein binds the signal molecule and is converted to its DNA-binding form, which...