Methods RNA-sequenced gene expression of Diffuse Large B-cell Lymphoma, Lung cancer, Liver cancer, Cervical cancer, and Testicular cancer were downloaded from the UCSC Xena database. Advanced-stage samples were normalized with early-stage samples to consider heterogeneity differences...
Survival analysis on gene expression (RNA-seq) in bladder cancer TCGA data - hamidghaedi/RNA-seq-survival-analysis
RNAseq and microarray methods are frequently used to measure gene expression level. While similar in purpose, there are fundamental differences between the two technologies. Here, we present the largest comparative study between microarray and RNAseq methods to date using The Cancer Genome Atlas (TCGA...
Relevant clinical data were downloaded from TCGA Prostate Cancer and TCGA Bladder Cancer databases. Heat maps of these genes were drawn in Xena Browser. Differential gene expression analyses with RNA-seq data in unit log(TPM + 0.001) for these genes were performed between these two groups ...
Characterizing cancer metabolism from bulk and single-cell RNA-seq data using METAFlux Metabolic reprogramming is a common indicator of the tumour microenvironment. Here the authors develop the METAflux framework to predict metabolic fluxes from single cell RNA-seq data. ...
摘要: MOTIVATION: Next-generation sequencing technology enables an entirely new perspective for clinical research and will speed up personalized medicine. In contrast to microarray-based approaches, RNA-Seq...关键词: Humans Oligonucleotide Array Sequence Analysis Gene Expression Profiling Sequence Analysis,...
Cooper, S (2012) mRNA-seq of single prostate cancer circulating tumor cells reveals recapitulation of gene expression and pathways found in prostate cancer... Wang,Xiangdong - Springer Netherlands 被引量: 2发表: 2015年 Next Generation Genomic Analyses in T-ALL Patients Identify Recurrent and Novel...
美國NIH資助的The Cancer Genome Atlas資料庫儲存有大量基因體資料包含RNA-seq,缺點就是裡面只有從TCGA 相關計畫出來的資料。 Rna-Seg Atlas則是目前有提供RNA-seq expression profiles的資料庫,但是其只含有一個data sets,11個檢體。 相對地,這次台灣清華大學建置的Cancer RNA-Seq Nexus資料庫裡頭有54組人類的癌細...
First, expression intensity from either microarray or RNA-seq is pre-processed for pairwise comparison between any of the two genes. 首先,从微阵列或RNA-seq的表达强度进行预处理,以便对两个基因中的任何一个进行两两比较。 Then, the relative expression value (0/1) is recorded as newvariables are...
miRNAs as targets for cancer treatment: therapeutics design and delivery Jasjit K. Banwait, Dhundy R. Bastola, in Advanced Drug Delivery Reviews, 2015 5.1.3 Expression data-based approaches With the advancement of the microarray and the RNAseq technologies, many gene expression studies have been ...