Differences between families in (socio-economic) environmental factors can also induce gene–environment correlations. Outcomes can, for example, be influenced by the parental genotype through parental (rearing) behavior and inherited socio-economic environments11. These indirect genetic effects have been ...
Offspring-parent correlations (rOP) and regression slopes (βOP) were computed by assigning a weight of one-half to the offspring-father and one-half to the offspring-mother pair (if both parents were available), and assigning a weight of one to the offspring-parent pair if only one parent...
environment correlation occurs when parents provide rearing environments to their children that are influenced by genes shared by parent and child. For example, parents genetically predisposed towardsubstance usenot only pass thatgeneticliability onto their children but may also create an environment whe...
Thereafter, the power by which the adjacency matrix will be computed from the correlation matrix is determined by soft thresholding [30]. The adjacency matrix is then computed from the adjacency matrix using that power. After that, wTOM scores are evaluated. After obtaining the wTOM/GTOMm ...
(Wang et al., 2014). The recurrent copy number gain regions in PVRLs that most frequently occurred onchromosome 1qfollowed by 18q and 19q were identified. There was a correlation between the gain of theIL-10gene located on 1q and the intravitreal IL-10 concentration. This suggests that ...
Distribution of correlation of gene expression to SPPR In order to understand how the correlation of gene expression to SPPR varied in different functional categories, T. reesei genes were mapped to five broad, mutually exclusive cellular categories: genes of the T. reesei metabolic model, genes ...
Chemical control has been the main measure for controlling walnut anthracnose, but it is limited by the pathogen’s resistance and the impact on environment, chemical control measures are limited [90,91,92]. Therefore, the breeding of disease-resistant varieties is of extreme interest. We ...
(GSEA) rank test (Fig.4c) reveals the significant correlation between the distribution of genes within the “early”, “intermediate” and “not silenced” clusters and their distance to the XIC, and recapitulates the observed distributions of the clusters over the X chromosome (Additional file1:...
For the variable selection method, the Spearman correlation was −0.0063. It appears that the ANOVA approach tends to rank overlapping gene sets similarly while the Bayesian variable selection approach does not. One illustrative example is the ‘Focal Adhesion’ pathway that contains 152 genes. It...
For example, the ADHD polygenic score is directly linked to the diagnosis of ADHD, so once genetic risk and the corresponding phenotype are covariates, their dependency is present in the model. Dependencies could also arise when gene-environment correlation (rGE) plays a role. rGE occurs when ...