Novel DNAs containing the regions which encode proteins have been directly cloned from cDNA libraries derived from the human adult whole brain, the human adult hippocampus and the human embryonic whole brain, the nucleotide sequences thereof have been determined, and their functions have been ...
The human Cranio Facial Development Protein 1 (Cfdp1) gene maps to chromosome 16q22.2-q22.3 and encodes the CFDP1 protein, which belongs to the evolutionarily conserved Bucentaur (BCNT) family. Craniofacial malformations are developmental disorders of particular biomedical and clinical interest, becaus...
Conceptual translation of the 2.4 kbp cDNA sequence reveals an open reading frame of 578 amino acids that is predicted to encode a 65-kDa protein with a pI of 8.4 (Fig. 1 B). This protein, AtTRP1, contains four clusters of basic residues (Fig. 1, B andC). The amino acid sequences...
suggesting a negative effect of this miR-1 on BDNF protein levels.68Similarly to miR-1, miR-206 shares the same predicted binding site within the 3′ UTR of the BDNF mRNA, and different
Annotation of the unigenes was carried out by BLASTX against nr, Swiss-Prot, KEGG and COG (E value <10-5) protein database. Information from proteins with the highest similarity to the given unigene was used to annotate the unigene function. Gene Ontology (GO) gene functional classification...
The researchers in the study carried out large-scale gene sequencing and then zeroed in on significant high-protein chromosomal regions, according to the survey. THP9 could encode an enzyme playing a significant role in the metabolism of nitrogen, according to the study. ...
or differences in transcription reaction rates. The higher complexity of humantranscriptome, as unraveled by the Encode project(101), also makes difficult to interpret gene-expression plasticity in terms ofRNAlevels. In any case, gene-expression analysis is one of the most fruitful approaches for th...
tfsroadmapgenerna-seqmotifgene-expressionregulationepigeneticsencodecellchip-seqhotspotplasticitytranscription-factor-bindingmotifsepigenomicsfimohaystack-biospecific-regionshaystack-pipeline UpdatedJun 21, 2022 HTML A python package and a set of shell commands to handle GTF files ...
These particular genes encode proteins with putative roles in fructose metabolism (PFKFB148), apoptosis and stress (SLK49), and brain development (PHGDH50), each of which stands to influence organismal behavior. One of these genes, 6-phosphofructo-2-kinase (PFKFB1), was the sole gene to ...
Gene expression is the generation of a functional gene product from the information encoded by a gene, through the processes of transcription and translation. Gene products are often proteins, however non-protein coding genes can encode functional RNA, including ribosomal RNA (rRNA), transfer RNA (...