The US Food and Drug Administration has approved the first gene-editing therapy ever to be used in humans, for sickle cell disease, a blood disorder that affects about 100,000 Americans, mostly black people. The agency on Friday also approved a second treatment using conventional gene therapy f...
The message that has emerged from all this talking is crystal clear: it is far too soon to attempt germline genome editing in humans – the process by which the genome of an individual is edited in such a way that the change is heritable. But on Monday came the news that a...
Since both haploinsufficiency and hyper-expression of FOXG1 cause diseases in humans, we reasoned that adding a gene under nonnative regulatory sequences would be a risky strategy as opposed to a genome editing approach where the mutated gene is reversed into wild-type. Here, we demonstrate that...
The first reported instance of germline gene editing in humans was bad science as well as bad ethics, according to a commentary publishing April 30 in the open-access journalPLOS Biologyby Haoyi Wang of the Institute of Zoology, Chinese Academy of Sciences (CAS) and Hui Yang of the Institutes...
What do we do now?: Responding to claims of germline gene editing in humansMegan Allyse PhDYvonne Bombard PhDRosario Isasi JD, MPHMarsha Michie PhDKiran Musunuru MD, PhDKelly E. Ormond MS, LCGCGenetics in Medicine
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This type of gene editing technology is already used every day in fields ranging from agriculture to drug development. The tools enable scientists to alter the DNA of living cells -- from plants, animals, and now, potentially, even humans -- more precisely than ever before. Think of it as...
It's done in an hour-long surgery under general anesthesia. Through a tube the width of a hair, doctors drip three drops of fluid containing the gene editing machinery just beneath the retina, the lining at the back of the eye that contains the light-sensing cells. ...
Some believe that gene editing could benefit HIV patients.80.不道德的81.另一些人担心,人们会利用基因编辑技术去制造“定制婴儿”82. 1)is a researcher who hope to make the world's firstgenetically edited babies.2)Julfan Savulescu from the University of Oxford told BBCNews.83. gene editing ...
The extent of achievement of the scientists using gene editing in humans highlights the need to develop ethical guidelines that regulate this area of research (Lanphier et al., 2015; Vogel 2015; Peng et al., 2016). Scientists currently suggest that a cure can be attained at the somatic cell...