Gene body coverage on average for each group.Benjamín, SigurgeirssonOlof, EmanuelssonJoakim, Lundeberg
Library and mapping quality was assessed by analysis of cumulative gene assignment diversity and gene-body coverage (Supplementary Figure 14e–h) using the QoRTs package54. In total, 89 nuclei passed these quality controls and were included for further analysis. Next, to improve statistical ...
If you are not going to use RSeQC 'geneBody_coverage.py', you can skip this step. 1_geneBodyCoverage.sh bash 1_geneBodyCoverage.sh $species $indir $outdir Arguments: $species - human 'hg38' or mouse 'mm10' (default='hg38') ...
kb away from the genes. In total, 61% of these SVs were substantially associated with expression changes of their SV genes, slightly less than 69% among the 27-genome assemblies. The SV presence was substantially associated with suppressed expression of 1,071 (55%) genes or promoted expre...
The term “housekeeping gene” refers to a gene used in the ordinary, day-to-day, metabolism of a typical or generic cell in the body, and that maintains constant expression, even when drugs are administered (160 From:Clinical Trials (Second Edition),2016 ...
proximal regions; gb up: upregulated in gene body region; gb down: downregulated in gene body region; gb unchanged: unchanged in gene body region).cIGV snapshot of an example that shows a concomitant increase of RNA transcription in promoter-proximal but no change in gene body uponHdac3...
Coverage profiles suggested that ASH1 and FSH normally bind close to the TSS of active genes, but are absent from promoter distal parts of the gene body. Deviating from this canonical observation, we found signals within gene bodies at a subset of active genes: predominantly, these genes fall...
The small size of the mtDNA affords a depth of coverage to sample total mtRNA and characterize subtle events or differences between samples [3]. Studies of whole cell-transcriptomes have allowed the initial profiling of mitochondrial transcriptomes in different tissues through the Illumina Body Tissue...
we adopted the STRING networks that integrated seven different functional interaction sources [14]. These networks also provide the widest coverage of species and genes among currently available network data (e.g., over 18,000 human genes). GScluster also provides analysis based on HIPPIE 2.0 netw...
Gene body region was defined as a region from the promoter end (+250 bp from the TSS) to the most commonly annotated transcript end for the corresponding gene (a transcript end which is supported by highest number of annotated isoforms). If multiple transcript ends had the same support, ...