The relationship between gene and chromosome mutations in cultured Chinese hamster cells exposed to aflatoxin B1: Velázquez, A., C. de Nava, R. Coutiño and I. Pulido Institute of Biomedical Research, National University of Mexico, Mexico City (Mexico)...
The very long strand of DNA which further contains many genes (hundreds to thousands) makes up a chromosome. The genes are arranged in a particular sequence and have a particular location on the chromosome (called its locus). In addition to DNA, chromosomes also contain many...
In addition, epigenetic control is responsible for X-chromosome inactivation in women that guarantees they have the same number of X-chromosome gene products as do men.9 mRNA Processing (Splicing) Splicing is the pre-mRNA processing mechanism by which introns are removed and exons are joined ...
Chromatin is highly organized within discrete chromosome territories, into compartments of active or inactive chromatin, self-interacting domains, and loops between specific loci (reviewed in refs. 1,2). However, the relationship between the three-dimensional (3D) organization of chromatin and the regu...
Extreme independent variation in the expression of pairs of HLA-associated transcripts (HLA-B/C, HLA-A/F and HLA-DRB1/DRB5) in macrophages was associated with HLA genotype. Correlation analysis indicated the downstream impacts of variation in the immediate early response to LPS. For example, ...
a technology referred to as SCRaMbLE (Synthetic Chromosome Rearrangement and Modification by LoxP-mediated Evolution). Several applications of SCRaMbLE for the improvement of industrial production traits have been reported in recent years, demonstrating the potential and importance of structural variation for...
[39–46]. Nevertheless, a clear association between promoter nucleotide sequences and chromosome territories was never hypothesized. The purpose of our work was to establish a possible functional significance of promoter sequences which may explain the dynamic relationship between different chromosome ...
In the presence of horizontal gene transfer (HGT), the concepts of lineage and genealogy in the microbial world become more ambiguous because chimeric genomes trace their ancestry from a myriad of sources, both living and extinct. We present the evolutio
(7 genes). Three RAV subfamily members were distributed on chromosomes 2, 9, and chromosome 10. Interestingly, some TFs with similar conserved sequences were located on the same chromosome. Similar patterns have been found in theA. thaliana[5], Chinese cabbage [30], and pepper genomes [34]...
D. et al. Molecular mechanisms and evolutionary processes contributing to accelerated divergence of gene expression on the Drosophila X chromosome. Mol. Biol. Evol. 32, 2605–2615 (2015). CAS PubMed PubMed Central Google Scholar Nica, A. C. & Dermitzakis, E. T. Expression quantitative ...