Regiospecific Synthesis of Bicyclo- and Heterobicyclo-gem-difluorocyclobutenes Using Functionalized Fluoroallenes and a Novel Mo-Catalyzed Intramolecular [... A Rhodium(I)- Catalyzed Formal Allenic Alder Ene Reaction for the Rapid and Stereoselective Assembly of Cross-Conjugated Trienes. J. Am. ...
copper catalytic systems were developed for the borylation ofgem-difluoroalkenes with B2pin2via dual C–F bond activation to afford multi-borylate libraries—1,2-alkyldiboronates, 1,1,2-alkyltriboronates and 1,1,1,2-alkyltetraboronates—by slightly tuning the reaction conditions. The advantages ...
中文翻译: 过渡金属催化宝石二氟烯烃官能化的最新进展。 gem-二氟化烯烃是易于获得的结构单元,可以进行功能化以提供广泛的氟化和非氟化产品。在此,我们回顾了最近(自 2017 年以来)过渡金属催化的这些特殊烯烃的转化,并总结了这些反应的一般反应模式。许多过渡金属催化的反应都会发生净 C−F 键官能化反应,以产生单...
Herein, we describe a novel and efficient photoredox catalytic radical addition/defluoroalkylation coupling reaction between primary amines and trifluoromethyl-substituted alkenes. A series of gem-difluoroalkenes were synthesized via C–N bond cleavage of α-3°, α-2°, and α-1° amines under vi...
The highly selective synthesis of spirobiindanes, alkenyl chlorides, and monofluoroalkenes via the cleavage of inert C(sp3)–F bonds in unactivated gem-difluoroalkanes using readily available and inexpensive aluminum-based Lewis acids of low toxicity is
This reaction has been applied to the synthesis of 3-gem-difluoro-2-phenylallylic amines and other functionalised gem-difluoroalkenes. 关键词: Trifluoromethylstyrene gem-difluoroalkenes organolithium reagents DOI: 10.1016/00404-0399(50)09334- 被引量: 76 年份: 1996 ...
A trifluoromethylalkynylation reaction of gem-difluoroalkenes with alkynyl sulfoxide by photoredox radical addition with good functional group tolerance in moderate to high yields, is developed for the synthesis of α-trifluoromethyl alkyne. This reaction features simple operation and inexpensive raw material...