Agents with film-forming protective properties, such as Gelsectan, represent a new alternative therapeutic option for the management of patients with irritable bowel syndrome.doi:10.2147/PPA.S318859Massimo BelliniGinevra BertiLeonilde BonfrateFlavia Ciranni...
Diarrhoea-predominant irritable bowel syndrome, Gelsectan, pea protein and tannins, prebiotics, mucoprotectants, xyloglucan, xylo-oligosaccharideBackgroundIrritable bowel syndrome (IBS) is highly prevalent and presents a clinical challenge. Gelsectan is a medical device containing xyloglucan (XG), pea ...
Gelsectan was evaluated in a recent double-blind study in which 60 patients were randomly assigned to receive XG + PPT + XOS or placebo for 28 days, then crossed over to the alternative treatment, and followed for a further 60 days. The patients enrolled were aged 18–65 years with a co...
Translational evaluation of Gelsectan effects on gut barrier dysfunction and visceral pain in animal models and irritable bowel syndrome with diarrheadoi:10.1002/ueg2.12681Livia Caroline LuccaNatália Piccoli BrusamarelloFernando FornariUnited European Gastroenterology Journal...
(A). The compounds of GELSECTAN®exert important properties in restoring leaky gut (B). The xyloglucan creates a protective film that protects the integrity of mucosal cells against pathogens, allergens and pro-inflammatory compounds. PPT complexes show also a mucoprotective activity. Xylo...