2.1 GC的添加提高了压缩模量 To determine the effects of GC on the mechanical properties of GelMA-GC hydrogels, compression test and swelling analysis were conducted with two different photo-cross-linking systems, Ru/SPS and LAP, respectively. GC significantly increased the CM of hydrogels in both ...
Swelling ability of hydrogels, which is influenced by hydrogel pore size, can indicate the degree of hydrophilicity and is an essential feature of the cornea. The measured mass swelling ration of the native cornea and pure GelMA hydrogel was 14.5 ± 0.59 and 16.7 ± 0.51 (The data...
Specially, hydrogel is a multi-component platform with a three-dimensional cross-linked network structure. It is insoluble in water, but has obvious swelling properties, and the mesh structure formed after cross-linking can carry a large number of water molecules. Cells can be embedded on the ...
To characterize the physical properties of the composite scaffold, the mechanical strength, swelling ratio and internal microstructure were tested. The biocompatibility of the GelMA/CMCS scaffold was evaluated by live/dead test and CCK-8. To evaluate the cell distribution, CD31 expression and ...
Finally, the hydrogel was freeze-dried and the porous scaffold were obtained. The scaffold samples were characterized via SEM, FTIR, mechanical compression test, swelling test and degradation test. The in vitro cellular responses to the GelMa/ES-HA composite scaffold were...
To determine the effects of GC on the mechanical properties of GelMA-GC hydrogels, compression test and swelling analysis were conducted with two different photo-cross-linking systems, Ru/SPS and LAP, respectively. GC significantly increased the CM of hydrogels in both photoinitiator groups (Figure1A...
The swelling ratio was calculated as follows: (Wwet – Wdry)/Wdry × 100%, where Wdry is the original weight and Wwet is after removal from PBS. 2.7. Degradation and Stability Test of the Conductive Hydrogel For the in vitro degradation test, rectangular samples were prepared. Dry ...
The solid construct was placed in the rheometer, and the storage modulus was recorded with a time sweep oscillatory test. 2.3. Hydrogel Swelling Polymerized GelMA hydrogels were incubated in water until equilibrium and weighed. The hydrogels were then frozen over night at −80 ◦C and ...
Thus, the shape of the printed objects was preserved visually, while the differences from the parameters specified in the software of the printer after printing could be associated with the ongoing polymerization of the hydrogel. It is also quite obvious that hydration (swelling) of the hydrogel ...
However, GelMA hydrogel alone does not provide the mechanical strength, osteogenic factors, and mineral ions, such as calcium and phosphorus, required for bone reconstruction. It also has the disadvantages of a long gelation time, short degradation time, and high swelling rate when used as a ...