2.1 GC的添加提高了压缩模量 To determine the effects of GC on the mechanical properties of GelMA-GC hydrogels, compression test and swelling analysis were conducted with two different photo-cross-linking systems, Ru/SPS and LAP, respectively. GC significantly increased the CM of hydrogels in both ...
Further, the hydrogel was lyophilized to obtain dry weight (Wd). The swelling ratio of the hydrogel was calculated by the follow equation:Swell ratio = (Ws − Wd) / Wd× 100% 2.5. Degradation test The degradation properties of hydrogels were evaluated in vitro by incubation in PBS or in...
Swelling ability of hydrogels, which is influenced by hydrogel pore size, can indicate the degree of hydrophilicity and is an essential feature of the cornea. The measured mass swelling ration of the native cornea and pure GelMA hydrogel was 14.5 ± 0.59 and 16.7 ± 0.51 (The data...
To characterize the physical properties of the composite scaffold, the mechanical strength, swelling ratio and internal microstructure were tested. The biocompatibility of the GelMA/CMCS scaffold was evaluated by live/dead test and CCK-8. To evaluate the cell distribution, CD31 expression and ...
1h). The swelling ratio of Fe2O3/GelMA hydrogels decreased with the amount of Fe2O3 nanoparticles, which may contribute to the increased cross-linking of hybrid hydrogel (Fig. 1i). Interestingly, the internal mechanical properties of these hydrogels were significantly improved by enhancing their...
Finally, the hydrogel was freeze-dried and the porous scaffold were obtained. The scaffold samples were characterized via SEM, FTIR, mechanical compression test, swelling test and degradation test. The in vitro cellular responses to the GelMa/ES-HA composite scaffold were ...
To determine the effects of GC on the mechanical properties of GelMA-GC hydrogels, compression test and swelling analysis were conducted with two different photo-cross-linking systems, Ru/SPS and LAP, respectively. GC significantly increased the CM of hydrogels in both photoinitiator groups (Figure1A...
placed in 50 mL centrifuge tubes with ultrapure water, after swelling for a certain time at 37 °C, the hydrogels were taken out, filter paper were used to absorb the free water on the surface of the hydrogels, after which the wet weight (Wt) of the hydrogel after swelling were measured...
Then the HDC hydrogel patch was measured using a fourier transform infrared reflection (FTIR) spectrometer (Nicolet iS50, Thermo Fisher). 2.1.6. Swelling and degradation experiments In order to assess the swelling behavior of HDC and HDC-bFGF patches, the samples were first freeze-dried to remov...
Thus, G-S hydrogel can maintain a moist healing environment in the wound bed for a long time with adequate degradation capacity, and is considered to be more suitable for skin wound dressing. The pore size, cell viability, cell growth state, swelling ratio, and mechanical properties were ...