Dataset Loaders Edit No data loaders found. You can submit your data loader here. Tasks Edit Drug Response Prediction Usage Number of Papers202120222023202420250123GDSC License Edit The data files are experimental and academic in nature and are not licensed or certified by any regulatory body. ...
总的来说就是较低的AUC值表明细胞对治疗的敏感性增加。如果我们想研究基因表达与药物敏感性的相关性，需要获取基因在不同细胞系中的表达谱和每个细胞系中各种药物的IC50或者AUC值。表达谱数据下载 点击download from GDSC1000 resourse 点击Dataset 下载后解压打开时这样，包含17393个基因和1019个细胞系 细胞系信息和药...
GDSC datasetDrug response prediction can infer the relationship between an individual's genetic profile and a drug, which can be used to determine the choice of treatment for an individual patient. Prediction of drug response is recently being performed using machine learning technology. However, ...
1)表达谱信息:Download from GDSC1000 resourse > Dataset("EXP"-"Preprocessed Cell-lines"-"RMA normalised expression data for cell-lines"-"RMA normalised basal expression profiles for all the cell-lines"-"Pathway Activity Scores") GDSC-3 第一列和第二列为基因名,后续为各个细胞系中对应的基因表达谱...
在Dataset中,选择相对较新的GDSC 2数据集的结果,就可以看到所有肿瘤(Pan-cancer)中EGFR突变与抗癌药物之间的相关性,对于具体的肿瘤我们也可以在Tissue specific analysis中进行修改。 ▲ 图中,每个圆圈代表一种抗癌药物,鼠标移至圆圈处即可显示该药物的具体信息,包括Drug,Samplesize,Effect,以及P-value。如结果显示,随...
在Dataset中,选择相对较新的GDSC 2数据集的结果,就可以看到所有肿瘤(Pan-cancer)中EGFR突变与抗癌药物之间的相关性,对于具体的肿瘤我们也可以在Tissue specific analysis中进行修改。 ▲ 图中,每个圆圈代表一种抗癌药物,鼠标移至圆圈处即可显示该药物的具体信息,包括Drug,Samplesize,Effect,以及P-value。如结果显示,随...
药物IC50以及AUC文件:GDSC1-dataset img ANOVA统计文件(可选):GDSC1-ANOVA img 基因在各个细胞系表达量的文件:Download from GDSC1000 resourse 或者依此检索后下载 处理下载后的数据 Step 1 - 使用perl程序-整理“expression”和“drug两个数据表格,”将表达数据+药物的IC50数据整理成,横行为细胞COSMIC的ID,列为IC...
GDSC Competition Copied from Samyak Jain (+197,-55)NotebookInputOutputLogsComments (0)historyVersion 1 of 1chevron_right Runtime play_arrow 5s Input DATASETS private-dataset private-dataset Language Python Table of Contents Basic PyTorch Neural NetworkVersion 8Create a model classLoad the iris data...