Effect of Granulocyte Colony Stimulating Factor (GCSF) on Survival in Patients with Acute Myeloid Leukemia (AML)doi:10.1182/blood-2024-211938Background: GCSF is a hematopoietic growth factor used in patients receiving chemotherapy, which is commonly used to prevent chemotherapy-induced neutropenia and ...
(MBP) tag at the N-terminus and expressed it as a soluble protein in the cytoplasm ofE. coli. We also conjugated PEG aldehyde to GCSF to make PEG-GCSF. The bioactivities of GCSF-Fc and PEG-GCSF were similar to native GCSF using the mouse M-NFS-60 myelogenous leukemia cell line. The...
We studied the nature of blast cells in 41 patients with acute leukemia following a previous primary myelodysplastic syndrome (MDS) by a combined multipara... R Garcíasanz,A Orfão,M González,... - 《Blood》 被引量: 128发表: 1991年 Myeloid dysplasia (MD): a hematological disorder prece...
3 麦文渊,林茂芳.高三尖杉酯碱诱导K562细胞凋亡的实验研究.中华血液学杂志,1998,19:375-376. 4 Harouseau JL, Wu DP. The use of GM-CSF and G-CSF in the treatment of acute leukemia. Leuk Lymphoma, 1995, 18:405-412.©2022 Baidu |由 百度智能云 提供计算服务 | 使用百度前必读 | 文库协议...
;CSF3R;G-CSF receptor;GCSFR;G-CSFR;Granulocyte colony-stimulating factor receptor Historical Background “Colony-stimulating factors” were first described in the 1960s as soluble agents that mediated the growth of colonies in soft agar from bone marrow cells. One of these was called granulocyte ...
Severe neutropenia remains among the most common complications associated with hematological diseases and their treatment, especially in the early poststem cell transplantation. Managing life-threatening infections associated with prolonged and profound
leukemia.BoneMarrow Transplant,1989,4:643—646 4 Dreger P,HaferlachT,EcksteinV,etc.G-CSF mobilized peripheral blood progenitor cellsfor allogeneictransplantation:safety,kinetics of mobilization, and composition of the伊m.Br J Haematol,1994,87:609—613 ...
Preliminary results from the US cancer and leukemia group B 50303 study showed that 25% achieved dose level 4 or beyond.11 In a study of patients with PMBCL, with a median age of 30 years, more than half of the Conclusion Our data support the use of peg-GCSF with front-line da-EPOCH...
Effect of cytosine arabinoside, hemoharringtonine and G-CSF for treating patients with heperleukocytic acute myeloid leukemia.Wu, DanZhang, XinhuaZhou, MinRan, QijieLi, JingyuanWang, JunXu, BiaoSong, SenhuaXie, HongLuo, Xiaojing
acute myeloid leukemia: JAK2Granulocyte colony-stimulating factor (GCSF) drives the production of myeloid progenitor and precursor cells toward neutrophils via the GCSF receptor (GCSFR, gene name). Children with severe congenital neutropenia chronically receive pharmacologic doses of GCSF, and30% will ...