Gastrointestinal stromal tumours are the most common mesenchymal neoplasm of the gastrointestinal tract and are highly resistant to conventional chemotherapy and radiotherapy. Such tumours usually have activating mutations in either KIT (75–80%) or PDGFRA (5–10%), two closely related receptor tyrosine...
Background-aim Gastrointestinal stromal tumours (GIST) are the most common mesenchymal neoplasms of the gastrointestinal tract, yet extremely rare since they account for less than 1% of all GI tumours, which may arise virtually in any part of the gastrointestinal tract. GISTs are typically defined ...
Gastrointestinal stromal tumours (GIST) have an incidence of ~1.2 per 105 individuals per year in most countries. Around 80% of GIST have varying molecular changes, predominantly mutually exclusive activating KIT or PDGFRA mutations, but other, rare subt
Gastrointestinal stromal tumours: from a surgical to a molecular approach International Journal of Cancer, 107 (2003), pp. 171-176 View in ScopusGoogle Scholar [15] R.P. Dematteo, M.C. Heinrich, W.M. El-Rifai, G. Demetri Clinical management of gastrointestinal stromal tumors: before and ...
Familial gastrointestinal stromal tumor with hyperpigmenta- tion: association with a germline mutation of the c-kit gene. Gastroenterology 2001;120:210–215. 78 Nishida T, Hirota S, Taniguchi M, et al. Familial gastrointestinal stromal tumours with germline mu- tation of the KIT gene. Nat ...
Genetic progression in gastrointestinal stromal tumors: mechanisms and molecular interventions. Oncotarget. 2017;8(36): 60589-60604. 11. Reddy P, Boci K, Charbonneau C. The epidemiologic, health-related quality of life, and economic burden of gastrointestinal stromal tumours. J Clin Pharm Ther. ...
摘要: Gastrointestinal stromal tumours (GISTs) are the most common mesenchymal neoplasms of the gastrointestinal tract. These tumours result from activating mutations in the KIT (CD117) proto-oncogene or pl关键词: Gastrointestinal stromal tumour GIST Mesenchymal neoplasms Tyrosine kinase inhibitor therapy ...
Gastrointestinal stromal tumours: ESMO clinical recommendations for diagnosis, treatment and follow-up[J]. Ann Oncol, 2009,20( Suppl 4) :64-67.Gastrointestinal stromal tumours:ESMO clinical recommendations for diagnosis,treatment and follow-up. Casali PG,Jost L,Reichardt P,Schlemmer M,Blay JY. ...
(redirected fromGastrointestinal stromal tumour) Dictionary Thesaurus Medical Encyclopedia gist the essential point of an action. Collins Dictionary of Law © W.J. Stewart, 2006 GIST, pleading. Gist of the action is the essential ground or object of it, in point of law, and without which ther...
Gastrointestinal stromal tumours (GISTs) negative for KIT (CD117 antigen) immunoreactivity. J Pathol 2004;202:430–438. Article CAS PubMed Google Scholar Duensing A, Joseph NE, Medeiros F et al. Protein kinase C theta (PKCtheta) expression and constitutive activation in gastrointestinal stromal ...