Cancers of the Esophagus and Small Bowel, Precancerous States of the Large Bowel, and Gastrointestinal Stromal TumorsEsophagusSmall bowelLarge bowelPositron emission tomography18F]Fluoro-2-deoxy-d-glucoseCompute
metabolism, proliferation and energy homeostasis. Significant increase of the expression of the mitochondrial biogenesis gene PGC-1α was observed in the precancerous region of colorectal cancer
A knock-in mouse model of gastrointestinal stromal tumor harboring kit K641E. Cancer Res 2005;65: 6631–6639. 28 Chen H, Hirota S, Isozaki K, et al. Polyclonal nature of diffuse proliferation of interstitial cells of Cajal in patients with familial and multiple gastrointestinal stromal tumours...
metabolism, proliferation and energy homeostasis. Significant increase of the expression of the mitochondrial biogenesis gene PGC-1α was observed in the precancerous region of colorectal cancer
Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal neoplasms of the gastrointestinal tract.Ever since the classification of GIST as an entity distinct from leiomyomas, leiomyosarcomas, etc., there has been an increased interest in defining their ...
Cancer cells express different antigens from normal cells due to genetic and epigenetic abnormalities. The immune system of the host uses these antigens to identify cancerous cells [15], and then attempts to destroy the cancer cells before a tumour develops, a process known as immune surveillance...
to the KIT protein which is linked to the growth of most Gastrointestinal stromal tumors and prevents the growth of cancer cells. In approximately 85 percent of patients, this drug can decrease the tumor or keep it from growing. If the tumor decreases sufficiently, surgery may not be necessary...
Gastrointestinal cancer (GIC) is the most prevalent and highly metastatic malignant tumor and has a significant impact on mortality rates. Nevertheless, the swift advancement of contemporary technology has not seamlessly aligned with the evolution of det
APOC1 was also significantly up-regulated in gastric cancer compared with para-cancerous and normal tissues, which was related to the clinical stage, tumor classification, and lymph node metastasis [53]. AP1S3, an adaptor protein complex, was considered as an oncogene binding to miR-4636 in ...
Also, in plasma of preoperative patients with gastric cancer (GC), the H19 plasma levels were higher than that of healthy controls. Conversely, there were no differences in H19 expression between cancerous tissues and paired noncancerous tissues [32]. Results from a meta-analysis showed that ...