Gastrointestinal stromal tumors (GISTs) are rare growths in the interstitial cells of Cajal present in the wall of the gastrointestinal tract. These tumors may be benign (noncancerous) or malignant (cancerous). Some may be benign at first but may later turn cancerous. GISTs make up to one...
Gastrintestinal stromal tumors constitute the group of most commonly occurring gastrointestinal tract sarcomas deriving from the precursor Cajala cells (responsible for peristalsis). The factor that initiates the cancerous process is the mutation in KIT or PDGFRA genes.In recent years there have ...
A gastrointestinal stromal tumor (GIST) is a type of tumor that occurs in the gastrointestinal tract, most commonly in the stomach or small intestine. The tumors are thought to grow from specialized cells found in the gastrointestinal tract called interstitial cells of Cajal (ICCs) or precursors ...
Gastrointestinal stromal tumors (GISTs) develop when the cells lining the digestive tract grow and divide uncontrollably, resulting in the formation of a mass of tissue or tumor leading to cancer. Some individuals suffering from gastrointestinal tumors may not experience any changes in their health, w...
A knock-in mouse model of gastrointestinal stromal tumor harboring kit K641E. Cancer Res 2005;65: 6631–6639. 28 Chen H, Hirota S, Isozaki K, et al. Polyclonal nature of diffuse proliferation of interstitial cells of Cajal in patients with familial and multiple gastrointestinal stromal tumours...
fibroblasts derived from a true non-cancerous origin, such as VH10 (skin) and hPS1 (pancreas) cell lines do not express JAM-A [24]. Of note, isolation of fibroblasts from normal pancreata destined for transplantation was unsuccessful. This raises the question whether tumor-adjacent fibroblasts...
Numerous studies have shown that CT colonography is nearly equal to traditional optical colonoscopy for detecting cancer and precancerous lesions. Many patients prefer CT colonography over colonoscopy because of perceived safety and convenience. The obvious disadvantage of CT colonography is for that ...
Cancerous stem cells share the same properties of self-renewal and differentiation as normal stem cells, and have a similar phenotype to adult stem cells i... B Wei,L Chen,R Li,... - 《Expert Review of Anticancer Therapy》 被引量: 33发表: 2010年 Stem cells in gastrointestinal cancers:...
Clin Cancer Res 17: 7584–7594. Kindblom LG, Remotti HE, Aldenborg F, Meis-Kindblom JM (1998) Gastrointestinal pacemaker cell tumor (GIPACT): gastrointestinal stromal tumors show phenotypic characteristics of the interstitial cells of Cajal. Am J Pathol 152: 1259–1269. Koelz M, Lense J,...
Gastrointestinal cancer (GIC) is the most prevalent and highly metastatic malignant tumor and has a significant impact on mortality rates. Nevertheless, the swift advancement of contemporary technology has not seamlessly aligned with the evolution of det