The genome of NoVs, which was first charac- terized in NV, contains a single-stranded positive sense RNA of 7.5–7.7 kb with three open reading frames (ORFs) and a poly A tail at its 3' end [19]. ORF1 encodes a polyprotein that is processed by viral protease 3CLpro into the ...
Our systematic review was in congruence with systematic reviews of probiotics in adults with viral gastroenteritis [55] and IBDs (mostly in ulcerative colitis) [56]. However, several recent systematic reviews showed no or minimum beneficial effects of probiotics in Crohn’s disease [56,57]. Some...