For liver and lung metastasis, metastatic burden was further quantified from single hematoxylin and eosin (H&E)-stained sections cut across the largest organ plane by counting individual lesions per section or estimating percentage of tumor area per organ slice. Histological analysis...
Thus, in this study, we designed SaB-Net to further improve the performance of GTS in CT images under training on the small-scale dataset. 3. Methodology This section describes the details of SaB-Net, including the network architecture, self-attention block, self-attention backward layer (SaB...
In the training dataset, the area under the curve (AUC) of the model was 0.929, the specificity was 0.806, and the sensitivity was 0.862. In the testing dataset, the model had an AUC of 0.957, specificity of 0.792, and sensitivity of 0.958. The AUC did not differ significantly between ...
External validation datasets were derived from the ACRG cohort (n = 300), SMC cohort (n = 432), and GSE26942 dataset (n = 217) within the GEO database. Of the GSE26942 and ACRG patients, 106 and 80, respectively, underwent standard adjuvant therapy with 5-Fluorouracil (5...
Examin- ation of a dataset (2014-Jan-12) from The Cancer Genome Atlas (TCGA) [32], through cBioPortal (cbioportal.org) [33], revealed that of 220 tumor samples, a 5 % ERBB2 mutation rate in diffuse, microsatellite-instable (MSI) and chromosome-instable (CIN) gastric cancer subtypes (...
External validation datasets were derived from the ACRG cohort (n = 300), SMC cohort (n = 432), and GSE26942 dataset (n = 217) within the GEO database. Of the GSE26942 and ACRG patients, 106 and 80, respectively, underwent standard adjuvant therapy with 5-Fluorouracil (5...
After extracting the gene expression data, we normalized the log2 median centered intensity levels (i) of each gene probe among all 913 human cancer cell lines of the dataset into values ranging from 0 to 100 by using the formula: normalized(i) = value(i) − m...
A retrospective dataset including CT images of 403 patients is assembled. Among them, 162 patients have more than 5-year survival. A CAD scheme is applied to segment gastric tumors depicted in multiple CT image slices. After gray-level normalization of each segmented tumor region to reduce image...
AandBGO-Biological process and KEGG-pathway analyses of DEGs from the GSE122130 dataset.CandDGO-Biological process and KEGG-pathway analysis of DEGs from the GSE14209 dataset.ENetwork-Analyst was used to analyze the PPI network of GRP75 and its interactors according to the KEGG database.FA hypo...
In the Caucasian dataset, there were significant stage differences according to ERBB2 expression. The significant p-value was in italic. (DOC 75 kb) Rights and permissions Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://...