EVs are observed in various body fluids, i.e., blood, saliva, urine, amniotic fluid, and ascites. EVs secreted from cancer cells play important roles in the formation of their environment, including fibrosis, angiogenesis, evasion of immune surveillance, and even metastasis. However, EVs in ...
The Ado basal levels in the interstitial fluid are between 30 and 300 nM [3]. However, under pathophysiological conditions, such as metabolic stress or during inflammation-associated tissue hypoxia or ischemia, Ado generation can exceed the removal capacity resulting in markedly increased extracellular...