Although the intestinal subtype of gastric cancer (GC) is most prevalent around the world, a relatively high prevalence of the diffuse subtype has been reported in some populations of Central American countries, including Guatemala. This study aimed to investigate whether differences exist in the ...
Gastric cancer remains one of the deadly diseases with poor prognosis. New classification of gastric cancers based on histologic features, genotypes and molecular phenotypes helps better understand the characteristics of each subtype, and improve early diagnosis, prevention and treatment. The objective of...
The pediatric gastric cancer cohort was defined by ICD9 and ICD 10 CM diagnoses attributable to primary (non-GIST, non-hematologic) solid tumors of the stomach limited to diagnosis priority < 5 and validated by filtering for supportive diagnoses. Demographic characteristics, comorbidities, before...
gastric cancer is categorized into four molecular subtypes: Epstein–Barr virus (EBV)-positive, microsatellite instability (MSI), genomically stable, and chromosomal instable tumors1. MSI is caused by underlying defect in the mismatch repair system (dMMR), and immunohistochemistry of mismatch repair ...
Epstein–Barr virus-associated gastric cancer Indel: Insertion and deletion SBS: Single base substitution SNV: Single nucleotide variant TCGA: The Cancer Genome Atlas WES: Whole exome sequencing References Yang J, et al. Epstein-Barr virus-associated gastric cancer: a distinct subtype. Canc...
Significance of Histological Response to Preoperative Chemoradiotherapy for Pancreatic Cancer White R, Xie B, Gotfried M, 2005, Prognostic significance of histologic response to preopera-tive chemoradiation of periampullary malignancies. Ann Surg ... Rebekah,R.,White,... - 《Annals of Surgical Oncolo...
Younger premenopausal women are more prone to developing ovarian metastases (OM) of gastric cancer (GC) than metastases of other organs; however, the molecular mechanisms remain unclear. Here we perform single-cell RNA sequencing on 45 tumor samples from
Intratumoral immune response to gastric cancer varies by molecular and histologic subtype. Am J Surg Pathol. 2019;43:851–60. Article PubMed PubMed Central Google Scholar Teh M, Lee YS. HLA-DR antigen expression in intestinal-type and diffuse-type gastric carcinoma. Cancer. 1992;69:1104–7...
Gastric stump cancer Gastric stump cancer (GSC) is a separate subtype of GC, defined as a carcinoma that occurs in the gastric remnant at least 5 years after the surgery for peptic ulcer.64 GSC rep- resents from 1.1% to 7% of all GCs (Figure 1), and males are more prone to them ...
(AUROC) of 0.77–0.9612,13,14. Moreover, deep learning models can predict the molecular subtype of muscle-invasive bladder cancer from H&E-stained slides15and the hormonal receptor status of breast cancer from histopathological images16. Herein, we hypothesize that a deep learning model may ...