Transfusion-related acute lung injury after the infusion of IVIG. Transfusion 2001;41:264-8. Orbach H, Katz U, Sherer Y, et al. Intravenous immunoglobulin: adverse effects and safe administration. Clin Rev Allergy Immunol 2005;29:173-84. Tai VM, Mitchell EJ, Lee-Brotherton V, et al. ...
Food and Drug Administration (FDA) has approved Gamunex, an intravenous immune globulin (IVIG) pooled from human blood, for the treatment of chronic inflammatory demyelinating polyneuropathy (CIDP). Gamunex is the first product to receive FDA approval as an orphan drug for this neurologic disease....
parenterally have tolerated doses of 3.0 to 9.0 g/kg/day for periods of several months without adverse effects.(21)Residualcaprylate concentrations in the final container are no more than 0.216 g/L (1.3 mmol/L). The measured buffer capacity is 35 mEq/L and the osmolality is 258 mOsmol/kg...