Patients who were disease-free had GGTP levels in the normal range, whereas patients with metastases had elevated levels. Serially increasing GGTP levels were associated with disease progression and death. Persons who remained free of disease had serial GGTP levels within the normal range. Further...
423 Serum γ-glutamyl transpeptidase (GGTP) levels are normal despite the elevation of serum alkaline phosphatase levels.437 Levels of GGTP in the liver are reported to be elevated.438 Serum GGTP could be used as a marker for Byler disease because normal values were found in 22 of...
A characterization of gamma-glutamyltranspeptidase in normal, perinatal, premalignant and malignant rat liver. 1. 1. γ-Glutamyltranspeptidase displays the following order of activity in tissues of the Fischer 344 rat: kidney ⪢ small intestine ⪢ cerebral cortex = testis > lung ⪢ liver = he...
Gamma glutamyltranspeptidase (GGTP) 1. Although present in many different organs, GGTP is found in particularly high concentrations in the epithelial cells lining biliary ductules. 2. It is a very sensitive indicator of hepatobiliary disease but is not specific. Levels are elevated in other conditi...
Even within a normal range of concentration, serum γ-GT has been reported to be related to the presence of diabetes17, 42, 48. However, our results did not support serum γ-GT activity as a predictor of T2DM in adolescents. Several possible explanations are as follows: First, epidemiologica...
A single dose of 3′-methyl-4-dimethylaminoazobenzene (3′-Me-DAB) produced an increase of GSH which, within a certain range, depended upon the amount of the carcinogen. In well differentiated, slowly growing hepatomas, the concentration of GSH approached the level in normal adult rat liver....
In contrast to hyperbilirubinemia, serum -GTP levels were relatively low, or within normal range. Microscopically, intracanalicular cholestasis, bile duct loss or atrophy and varying degrees of fibrosis were found in all of the cases, whereas giant cell formation of hepatocytes was detected in three...
GABAB receptors are essentially presynaptic, usually coupled to potassium or calcium channels, and they function via a GTP binding protein. In neural and nonneural tissues, GABA is metabolized by three enzymes--glutamic acid decarboxylase (GAD), which produces GABA from glutamic acid, and the ...
A low or normal GGT test result indicates that it is unlikely that you have liver disease or have consumed any alcohol. GGT is very sensitive and can be increased when you don’t have symptoms. This may be temporary, perhaps due to medications you are taking or if you drink alcohol withi...
Since in vivo CSR is defective in all patients and IgM levels can be in the normal range in some individuals (especially after Ig substitution), we suggested that the term “CSR deficiency” was more appropriate (12). Interestingly, almost all patients initially reported in the literature were...