1 115>G H39D ND [202] 1 120-121delC,T Truncated protein Inactive [51] 1 222>A Y74X Inactive [202] 1 295delT Truncated protein Inactive [203] 1 474-475insT/508-510delTTC Truncated protein/F170del Inactive/Inactive [204,205] 1 508-510delTTC F170del Inactive [70,...
Normally, GGT is present in low levels, but when the liver is injured, the level can rise. GGT is usually the first liver enzyme to rise in the blood when any of the bile ducts that carry bile from the liver to the intestine become obstructed, for example, by tumors or stones. This...
Serum gamma-GT activity was measured, using a commercially available kit in blood and colostrum/milk samples. Correlations were carried out between immunoglobulin and gamma-GT levels. Regression models (simple and multiple) were calculated with significant data. Linear correlation was determined between...
gamma-Glutamyl transpeptidase-cellular expression in populations of normal human mononuclear cells and patients suffering from leukemias. The expression of the ectoenzyme γ -glutamyl transpeptidase (EC2.3.2.2., γ GT) was investigated by flow cytometry on populations of peripheral blood mono... M T...
The γ-GT levels increased significantly in proportion to the number of elements of MS (P0.01). Multiple stepwise regression analysis showed that triglycerides, waist circumference, menopausal status, 2h postprandial blood glucose and body mass index were independent influencing factors of γ-GT levels...
passes the membrane of the blood vessels and enters into thebrain tissue, where it decomposes and decays with its 6.0 h half-life,allowing detailed imaging of the brain. The average absorbed whole body dose in such a SPECT scan is about 0.01 Sv.Figure 9.16(right) shows three133Xe gamma-cam...
Glial cells have been shown to induce enzyme activities, which are characteristically high in brain capillaries, in cerebral and non cerebral endothelial cells in culture. We evaluated the activity of gamma-glutamyl transpeptidase (gamma-GT) in freshly isolated (ex vivo) bovine blood (BEC) and ...
Regarding γ-GT quartiles, body mass index (BMI), blood pressure, total cholesterol, aspartate transaminase (AST), and alanine transferase (ALT) were increased from lowest quartile to highest quartile (Table 2). Glycemic status and fasting plasma glucose value was higher for greater quartile of ...
l-BSO has proven its efficacy as an enhancer of the antitumor activity of the alkylating agent melphalan in Phase I and II clinical trials, while other clinical trials have shown that administration of l-BSO depletes intracellular GSH levels in circulating white blood cells as much as 60–80%...
H. et al. Demonstration of an interferon gamma-dependent tumor surveillance system in immunocompetent mice. Proceedings of the National Academy of Sciences of the United States of America 95, 7556–7561 (1998). 5. Ishikawa, T. et al. Whole blood interferon-gamma levels predict the therapeutic...