Blood Chemistry Rats received intraperitoneal injections of 150 mg/kg of either pyrene or its ozonated derivatives, which produce more severe effects than pyrene itself. One rat treated with pyrene and one treated with ozonated pyrene died between 48 and 72 hours post-treatment. Treated an...
The effect of gamma irradiation on blood 中国输血杂志
Microglia, the resident immune cells of the brain, regulate neuroinflammation which can lead to secondary neuronal damage and cognitive impairment under pathological conditions. Two of the many molecules that can elicit an inflammatory response from microglia are lipopolysaccharide (LPS), a component of ...
aThe production of melanin by the isolated fungi. F10 was found to have the superior melanin yield than the other strains. Data are analyzed using one-way analysis of variance (ANOVA) followed by Duncan’s multiple range test that represented by the letters (a,b, c, d). The same letters...
For analyzing activity upregulated by interferon-gamma (or monokine induced by interferon-gamma) using peripheral blood mononuclear cells; drug screeningdoi:US7897357 B2Here, we describe a sensitive and specific assay and kit for the detection of chemokines having activity that is upregulated by Th-...
2.3. Intraperitoneal Glucose Tolerance Test For intraperitoneal glucose tolerance test (GTT), mice were fasted for 12 h before being administered a glucose load (2 g/kg, i.p.). Blood samples were collected from the tail vein at 0, 15, 30, 60, 120 min after glucose injection, and blood...
Researchers also showed that suppressing NFκB (p65) protein synthesis and increasing PPARγ gene and protein expression helped magnesium administration to decrease blood glucose levels in diabetic animals [68]. Recently, one group showed that telmisartan, besides its role as an anti-hypertensive drug...
Pouliot, M.; James, M.J.; McColl, S.R.; Naccache, P.H.; Cleland, L.G. Monosodium urate microcrystals induce cyclooxygenase-2 in human monocytes.Blood2012,91, 1769–1776. [Google Scholar] [CrossRef] Schlesinger, N.; Moore, D.F.; Sun, J.D.; Schumacher, H.R. A survey of curre...
The pathogenesis of atopic dermatitis (AD) is multifactorial, including immune dysregulation and epidermal barrier defects, and a novel therapeutic modality that can simultaneously target multiple pathways is needed. We investigated the therapeutic effec