GBL is classified as a Schedule I controlled substance, making it illegal in the US. Don't confuse GBL with Gamma-hydroxybutyrate (GHB) or 1,4-Butanediol. These chemicals are related but are not the same. Uses & Effectiveness We currently have no information for GAMMA BUTYROLACTONE (GBL) ...
Gamma-Butyrolactone (γ-butyrolactone) is a small molecule compound that is designed to inhibit the activity of GCN5. It is inspired by the theory that it should have hydrogen-bond acceptor properties for Cys177 and polar group interaction with Glu173 in GCN5, while also possessing an aliphatic...
In Phase 1, one of four doses of either gamma-butyrolactone or sentobarbital was injected before sessions. Both drugs increased lever pressing rates during the shocked component of the schedule at doses which did not affect lever pressing rates during the unshocked component. In Phase 2, one ...
Gamma butyrolactone (GBL) and 1,4-butanediol are analogs of GHB that can be substituted for it. Once ingested, these analogs convert to GHB and produce identical effects. GBL, an industrial solvent, is used as an immediate precursor in the clandestine production of GHB. The FDA has issued ...
纬-Hydroxybutyrate (GHB) is a DEA Schedule I drug of abuse commonly spiked into beverages to incapacitate victims of sexual assault. GHB is a challenging drug for analysis by GC/MS because of its small size, charged nature, low volatility, and intramolecular esterification leading to 纬-...
Apart from GHB itself, its prodrugs such as gamma-butyrolactone (GBL) (Figure 1) and 1,4-butanediol have also been deemed as date rape drugs (Mason & Kerns, 2002). GBL and 1,4-butanediol are intrinsically inactive under the pharmacological condition; however, they can be easily metabolized...
Concerned about the scale of the problem of the use, by predators, of licit and illicit substances, both under international control and not under international control, inter alia, alcohol (in fruit drinks, beer, wine and spirits), alprazolam # butanediol, gamma-butyrolactone, cannabis, chloral...
Baker LE, Van Tilburg TJ, Brandt AE, Poling A (2005) Discriminative stimulus effects of gamma-hydroxybutyrate (GHB) and its metabolic precursor, gamma-butyrolactone (GBL) in rats. Psychopharmacology (Berl) 181:458-466. :Baker, LE, Tilburg, TJ, Brandt, AE, Poling, A (2005) Discriminative ...
γ-Butyrolactones are a very common structural element in organic compounds, present in about 10% of all natural products [1,2]. A wide variety of naturally occurring mono-, di- and trisubstituted monocyclic γ-butyrolactones are known, but they are also found as part of more complex framewo...