网络功能增强型突变;功能获得性突变 网络释义
gain-of-function mutation名词解释 gain-of-functionmutation名词解释gain-of-functionmutation是指一种突变，使得一个基因获得了新的功能。这种突变可能是由于DNA序列的改变，导致基因表达产物的结构和功能发生变化，从而产生了新的功能。这种突变通常与疾病的发生有关，如癌症、神经退行性疾病等。在基因治疗中，gain-of...
gain-of-function mutation 【网络】获得性突变；功能增强突变；功能增强型突变 A gain-of-function mutation of arabidopsis lipid transfer protein 5 disturbspollen tube tip growth and fertilization.拟南芥一个脂质转移蛋白5的功能获得性突变体破坏了花粉管的顶端运输和受精作用。仅供参考 ...
1) gain-of-function mutation 功能获得突变1. Comparing with clas-sical T-DNA knock-out mutagenesis technology by the loss-of-function mutation, the activation T-DNA tagging technique based on the gain-of-function mutation has its own particular advantages, mainly characterized by producing dominant...
Zhu,Z.X,Liu,Y,Liu,S.J,Mao,C.Z,Wu,Y.R,Wu,P.A gain-of-function mutation in OslAA11 affects lateral root development in rice.Mol.Plant. 2012Zhu,Z.X,Liu,Y,Liu,S.J,Mao,C.Z Wu,Y.R and Wu,P. A gain-of-function mutation in OslAA11 affects lateral root development in rice[J...
Functional consequences of SCN1A mutation have been divergent and confusing. Initial gain-of-function effects for the Q1489K and L1649Q mutations, when testing the mutations in the closely related NaV1.5 channel subunit protein, were contradicted when the mutations were tested in the (proper) NaV...
Related to gain-of-function mutation:back mutation,genetic mutation,gene mutation,conditional mutant mu·ta·tion (myo͞o-tā′shən) n. 1.The act or process of being altered or changed. 2.An alteration or change, as in nature, form, or quality. ...
1. Position of the mutation is according to GRCh37 (hg19). MP1, mother of P1; FP1, father of P1; MP3, mother of P3; FP3, father of P3. e, Evolutionarily conservation of MIR140 in different species; miRNA hairpin sequence is highlighted in gray. The second nucleotide in miR-140-5p...
mutation, in biology, a sudden, random change in a gene, or unit of hereditary material, that can alter an inheritable characteristic. Most mutations are not beneficial, since any change in the delicate balance of an organism having a high level of adaptation to its environment tends to be ...
loss-of-functionmutationsandgain-of-functionmutations.1Aloss-of-functionmutationis‘amutationthatresultsinreducedorabolishedproteinfunction’.2Again-of-functionmuta-tionhasbeende nedas‘amutationthatconfersneworenhancedactivityonaprotein’.3Agoodunderstandingofthesetwotypesofmutationscanbegainedbyexaminingmutations...