实验中 经常会发现过表达和缺失的表型并不对立，其代表的意义也不一样。我认为一般以loss of function...
生物学与医学研究中，"gain-of-function"（增强型功能）与"loss-of-function"（丧失型功能）是描述基因或蛋白质变异对生物体影响的术语。Gain-of-function变异导致基因或蛋白质功能增强或出现新功能，可能改变蛋白质表达水平、活性或时间、位置表达。此类变异可引发异常现象，如细胞增殖增加、代谢率提升或信...
aDozens of tumor suppressors that 许多肿瘤遏抑器那[translate] ahave been discovered through their characteristic inactivation 通过他们的典型钝化作用被发现了[translate] athrough gain- or loss-of-function experiments in mice. 通过获取或损失作用实验在老鼠。[translate]...
求翻译:through gain- or loss-of-function experiments in mice.是什么意思?待解决 悬赏分:1 - 离问题结束还有 through gain- or loss-of-function experiments in mice.问题补充:匿名 2013-05-23 12:21:38 通过对小鼠的收益或损失的功能实验。 匿名 2013-05-23 12:23:18 匿名 2013-05-23 12:...
Gain- and loss-of-function Lyn mutant mice define a critical inhibitory role for Lyn in the myeloid lineage To investigate the role of the Lyn kinase in establishing signaling thresholds in hematopoietic cells, a gain-of-function mutation analogous to the Src Y52... KW Harder,LM Parsons,J ...
gain-and loss-of-function mutations in zat10 enhance the tolerance of plants to abiotic stress R Mittler,Y Kim,L Song,... 被引量: 0发表: 2017年 Systemic and Intracellular Responses to Photooxidative Stress in Arabidopsis As the sun tracks daily through the sky from east to west, different...
Gain-of-function mutation has not been frequently observed in rice plants, thus, the mutants can be used to identify loci of novel genes for the regulation of disease resistant response. 展开 关键词: Gain-of-function gamma-ray loss-of-function rice mutants ...
Loss-of-function and gain-of-function mutations of calcium-sensing receptor: functional analysis and the effect of allosteric modulators NPS R-568 and NPS ... Loss-of-function and gain-of-function mutations of calcium-sensing receptor: functional analysis and the effect of allosteric modulators ...
Evolution of New Hormone Function: Loss and Gain of a Receptor The vertebrate proglucagon gene encodes three glucagon-like sequences (glucagon, glucagon-like peptide-1 [GLP-1], and glucagon-like peptide 2 [GLP-2]) that... DM Irwin,K Wong - 《Journal of Heredity》 被引量: 48发表: 2005...
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