Disclosed herein are complexes of gadolinium metal, ligand and meglumine that are substantially free of non-aqueous solvents. In particular, solvent-free complexes of 1) gadopentetate dimeglumine and 2) gadoterate meglumine are disclosed and methods of their preparation are disclosed. In addition, ...
Intrathecal injectionof gadolinium has been advocated for the evaluation of patients with suspected cerebrospinal fluid (CSF) leaks, and appears to be more sensitive than CT myelography for this purpose. Typically about 0.3-0.5 mL of a 0.5Mgadolinium contrast (e.g., Gd-DTPA) is injected into ...
Structurally, gadolinium-containing contrast agents can be divided into two groups based on the type of ligand.Linear agentshave an elongated organic molecular ligand that wraps around the ion.Macrocyclic agentsform a cage-like ligand structure with the ion trapped in a preformed central cavity. Both...
Relaxivity is a measure of the degree to which a given amount of contrast agent shortens T1 or T2. This is obviously a very important metric as accelerated relaxation is the main purpose of administering contrast! Higher values are better. Higher relaxivities are associated with larger ligands ...
Deep Learning Enables Reduced Gadolinium Dose for Contrast-Enhanced Brain MRI (Journal of Magnetic Resonance Imaging 2018) 这是一篇医学图像增强的论文,介绍了研究人员正在使用人工智能来减少MRI检查后留在体内的造影剂的剂量。 提出背景 钆(gá,gadolinium)是一种用于对比材料的重金属,可增强MRI上的图像,作为一...
CLINICAL PICTURE Gadolinium Contrast in the Bladder: A Malignant Mimic James Kovacic, Jonathan Kam, Edward Latif In affiliation with the Division of Surgery and Anaesthesia, Department of Urology, Gosford District Hospital A 50-year-old female presented to hospital with diplopia and unsteady gait...
TECHNOLOGIST PRESENTATION Open AccessGadolinium contrast agents: over exposure?Robert W Biederman * , Ronald B Williams, Mark Doyle, June A Yamrozik, Moneal Shah, Geetha Rayarao,Sirikarn NapanFrom 19th Annual SCMR Scientific SessionsLos Angeles, CA, USA. 27-30 January 2016BackgroundMRI has dram...
These are the most commonly used contrast agents in MRI. Gadolinium has a predominant T1 effect and will produce an enhancement in T1.Fat signal suppression and enhancement after Gadolinium injection in breast MRI a. T1 weighted axial slice with fat saturation, before Gadolinium injectionb. T1 ...
Solvent-Free Gadolinium Contrast Agents 申请(专利)号: US201715855570 申请日: 2017-12-27 专利号: US2018185521A1 公开公告日: 2018-07-05 主分类号: A61K49/18 分类号: A61K49/18; A61K49/10 申请权利人: INVENTURE, LLC 发明设计人: RICHARD DESLAURIERS; JONATHAN BALFOUR; MICHAEL MILBOCKER 公开国...
英文:Late Gadolinium Enhancement(LGE) 中文:晚期钆增强 例句:Late gadolinium enhancement (LGE) is a method where cardiovascular magnetic resonance (CMR) images are obtained after the administration of gadolinium contrast material that accumulates into...