Neurontin is the trade name for the generic drug gabapentin. It is useful as an anti-epileptic drug and as an analgesic, particularly for pain of the neuropathic or neurogenic type. (pain from irritation or inflammation of nerves). When used for controlling epilepsy, it is usually used in co...
Group 1 patients received Gabapentin monotherapy while Group 2 patients received combined therapy of gabapentin and Methylcobalamin. Variables such as age, gender, weight, BMI, type of drug used and pain score were noted in proformas and data was then analysed with SPSS (VERSION 16).Results: ...
5.1 Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)/Multiorgan Hypersensitivity Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS), also known as multiorgan hypersensitivity, has occurred with gabapentin. Some of these reactions have been fatal or life-threatening. DRESS typically...
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS), also known as multiorgan hypersensitivity, has occurred with Gabapentin. Some of these reactions have been fatal or life-threatening. DRESS typically, although not exclusively, presents with fever, rash, and/or lymphadenopathy, in associati...
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The operator was blinded to the treatments (type of drug administered). The drugs and methylcellulose were purchased from Sigma- Aldrich Corp (St. Louis, MO, USA). The rats from the collagenase group were further divided into four subgroups depending on the treatment received from days 15 to...
Inhibition of K(+)-evoked glutamate release from rat neocortical and hippocampal slices by gabapentin. Gabapentin (Neurontin ®) has preclinical and clinical efficacy as an anticonvulsant, antihyperalgesic, anxiolytic, and neuroprotective drug. Since l-glu... DJ Dooley,CA Mieske,SA Borosky - 《...
Gabapentin is an antiepileptic drug that is structurally related to GABA and has a novel mechanism of action. It is effective for patients who have failed to respond to other medications and has a relatively mild side-effect profile. AI generated definition based on:Comprehensive Medicinal Chemistry...
(2004) 4.Gee, N.S., Brown, J.P., Dissanayake, V.U.K., et al.The novel anticonvulsant drug, gabapentin (neurontin), binds to the α2δ subunit of a calcium channelJ. Biol. Chem.271(10)5768-5776(1996) 5.Goa, K.L., and Sorkin, E.M.Gabapentin. A review of its ...
When prescribing gabapentin, carefully evaluate patients for a history of drug abuse and observe them for signs and symptoms of gabapentin misuse or abuse (e.g., self-dose escalation and drug-seeking behavior). The abuse potential of gabapentin has not been evaluated in human studies. 9.3 ...