The ROC analysis showed that the AUC for [68Ga]Ga-P16-093 PET/CT predicted true positive and false positive lesions were significantly higher than [68Ga]Ga-PSMA-11 PET/CT and dynamic contrast material–enhanced MR imaging. Conclusions: Results of this multimodal, cross-scale comparisons has ...
This study was prospectively designed to evaluate the early dynamic organ distribution and tumor detection capability of [ 68 Ga]Ga-P16-093, which was compared with [ 68 Ga]Ga-PSMA-617 in the same group of recurrent prostate cancer patients.Twenty patients with recurrent prostate cancer were enr...
Purpose This study was prospectively designed to evaluate the early dynamic organ distribution and tumor detection capability of [Ga-68]Ga-P16-093, which was compared with [Ga-68]Ga-PSMA-617 in the same group of recurrent prostate cancer patients. Methods Twenty patients with recurrent prostate ...
[68Ga]Ga-P16-093This study was undertaken to evaluate radiation dosimetry for the prostate-specific membrane antigen targeted [ 68 Ga]Ga-P16-093 radiopharmaceutical, and to initially assess agent performance in positron emission tomography (PET) detection of the site of disease in prostate cancer ...
[68Ga]Ga-P16-0932-[18F]FDGClear cell renal cell carcinomaPET/CTPurpose This pilot study was prospectively designed to evaluate and compare the diagnostic value of PET/CT using a PSMA-specific tracer [68Ga]Ga-P16-093 and a glucose metabolism probe 2-[18F]FDG in clear cell renal cell ...
In addition, the SUVmax of the primary tumor on [68Ga]Ga-P16-093 and 2-[18F]FDG PET/CT was significantly correlated with pT stage (for [68Ga]Ga-P16-093,r=0.550,P=0.008; for 2-[18F]FDG,r=0.514,P=0.014) and WHO/ISUP grade (for [68Ga]Ga-P16-093,r=0.566,P=0.006; for 2-...
Further, 68Ga-P16-093 PET/CT exhibited significantly higher SUVmax of matched tumors (18.3 ± 14.4 vs 13.9 ± 11.8, P < 0.001). Besides, the SUVmax of high-risk patients (based on D'Amico classification) on 68Ga-P16-093 PET/CT was significantly higher than that of low- and ...
Further, 68Ga-P16-093 PET/CT exhibited significantly higher SUVmax of matched tumors (18.3 ± 14.4 vs 13.9 ± 11.8, P < 0.001). Besides, the SUVmax of high-risk patients (based on D'Amico classification) on 68Ga-P16-093 PET/CT was significantly higher than that of low- and ...
Kit-based preparation of [ 68 Ga]Ga-P16-093 (PSMA-093) using different commercial 68 Ge/ 68 Ga generatorsHaiyan Hong aGuochang Wang bKarl Ploessl dZhihao Zha dJie Zang bZhaohui Zhu bLin Zhu aHank F. Kung c d
For the remaining four subjects, [68Ga]Ga-P16-093 PET/CT findings would have produced no change in surgical plans. Importantly, no patient had a positive margin on the side of the prostate where [68Ga]Ga-P16-093 PET was negative. Conclusions: [68Ga]Ga-P16-093 appears useful for pre-...