Conclusion The preliminary MRI-based nomogram could be used to discriminate the Ki-67 index in well-differentiated G1/2 PanNETs.doi:10.1177/0284185119840212Haitao SunShilong ZhangKai LiuJianjun ZhouXingxing WangTingting ShenXiaolin WangActa Radiologica
It is a radiopharmaceutical of [177Lu]Lu-DOTA-TATE with an activity of 7.4 GBq used to treat non-operable or metastatic, progressive, well-differentiated (G1 and G2) gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs), with confirmed somatostatin receptor expression in adults [20]. It is...
Once cells have terminally differentiated, they have a specialized function and no longer divide. Most tissues are made up of non-dividing cells. Thus normal cell proliferation is tightly controlled to ensure that only the necessary cells divide. There is also a careful balance between cell ...
well differentiatedBackground The objective of the current study was to identify the risk of early vs late recurrence of well‐differentiated (G1) neuroendocrine liver metastasis (NELM) after curative‐intent resection. Methods Patients who underwent curative‐intent resection for well‐differentiated NE...
The aim of the present guidance paper was to update the previous ENETS guidelines on well‐differentiated gastric and duodenal neuroendocrine tumours (NETs), providing practical guidance for specialists in the diagnosis and management of gastroduodenal NETs. Type II gastric NETs, neuroendocrine...
P1136 Introduction: 177Lu-DOTATATE peptide receptor radionuclide therapy (PRRT) is routinely administered to patients with progressing, disseminated, well-differentiated neuroendocrine tumors (NETs) on a fixed activity/cycle basis (4 cycle x 7.4 GBq/cycle). Patient-specific dosimetry after each cycle ...
The present study aimed to investigate the value of diffusion-weighted magnetic resonance imaging (DWI) in the grading of well-differentiated pancreatic neuroendocrine tumors (PanNETs). A total of 44 patients with histologically proven well-differentiated PanNET [grade 1 (G1) and grade 2 (G2) ...
Background The pathological classification of pancreatic neuroendocrine neoplasms (PanNENs) has been revised based on the World Health Organization (WHO) 2017 classification. Well-differentiated PanNENs were previously classified as G1, G2, or G3 according to the Ki-67 labeling index (LI), which ...
Conclusions PRRT is very effective in well-differentiated midgut NET with a high disease control rate (90%) and long progression-free survival (median 31 mo). Independent predictors of long-term outcome are the Ki67-based tumor grading and plasma CgA level.Amir Sabet...