1 细胞周期包括细胞分裂间期(G1期、S期、G2期)和分裂期(M期)两个阶段,细胞周期检查点(checkpoint)是细胞周期中的一套保证核DNA复制和染色体分配质量的检查机制,是一类负反馈调节机制。当细胞周期进程中出现异常时,这类调节机制就被激活,及时地中断细胞周期的运行。待细胞修复或排除故障后,细胞周期才能恢复运转。如图...
The role of G1 and G2 checkpoint control proteins involved in cell cycle arrest following treatment with the HSP90 inhibitor 17AAGcirculating cellsChromogranin A transcriptsneuroendocrine carcinomaHigh grade lung neuroendocrine carcinomas, like small and large cell neuroendocrine carcinomas, pose ...
百度试题 结果1 题目细胞周期中,在G1/S和G2/M处都有检验点(checkpoint)。相关知识点: 试题来源: 解析 正确细胞周期进程中,包括许多检验点,以保证细胞的正常增殖分裂。反馈 收藏
In summary, this study suggests that p21(Waf-1) regulates the ultraviolet-B-induced G2/M checkpoint through p53, and the G1 checkpoint partially through p53. p21(Waf-1) does not significantly regulate DNA repair in ultraviolet-irradiated keratinocytes, however. 展开 ...
Both agents also increased checkpoint kinase (Chk)2 phosphorylation at Thr68 and Ser19 sites, which is known to phosphorylate Cdc25C at Ser216 site. Chk2-specific small interfering RNA largely attenuated the silymarin and silibinin-induced G2-M arrest. An increase in the phosphorylation of ...
细胞周期中,在G1/S和G2/M处都有检验点(checkpoint)。 查看答案更多“细胞周期中,在G1/S和G2/M处都有检验点(checkpoint)。”相关的问题 第1题 全体施工人员每天天要对班组工人进行施工要求、作业环境的安全交底。() 全体施工人员每天天要对班组工人进行施工要求、作业环境的安全交底。() 点击查看答案 ...
checkpointand the DNA integrity [333,334]. Moreover, a molecular reciprocal activation between PLK1 and N-MYC was reported, which leads, among other factors, to the reduced degradation of N-MYC,cyclin E, and Mcl1 and reinforces MYC-regulated oncogenic programs [335]. Recently, it was also ...
Silymarin and silibinin cause G1 and G2|[ndash]|M cell cycle arrest via distinct circuitries in human prostate cancer PC3 cells: a comparison of flavanone silibinin with flavanolignan mixture silymarin 机译:水飞蓟素和水飞蓟宾通过不同的途径导致人前列腺癌PC3细胞中的G1和G2 | n || M细胞周...
p53 controls both the G2/M and the G1 cell cycle checkpoints and mediates reversible growth arrest in human fibroblastsWild-type p53... ML Agarwal,WR Taylor,GR Stark,... - 《Proceedings of the National Academy of Sciences》 被引量: 1836发表: 1995年 p53 controls both the G2\\/M and...
H. Siddik, "The impact of S- and G2-checkpoint response on the fidelity of G1- arrest by cisplatin and its comparison to a non-cross-resistant ... G He,K Jian,AR Khokhar,... - 《Gynecologic Oncology》 被引量: 85发表: 2011年 The impact of S- and G2-checkpoint response on the...