Learn about the G0 phase of the cell cycle. Review the cell cycle and understand the role of the G0 phase in it. Know why the G0 phase is important...
Wiecek, A.J., et al., Genomic hallmarks and therapeutic implications of G0 cell cycle arrest in cancer. Genome Biol, 2023. 24(1): p. 128.
Valentin M, Yang E (2008) Autophagy is activated, but is not required for the G(0) function of BCL-2 or BCL-x(L). Cell Cycle 7(17):2762–2768. : 10.4161/cc.7.17.6595Valentin, M., and Yang, E. (2008). Autophagy is activated, but is not required for ...
Genome Biology (2023) 24:128 https://doi.org/10.1186/s13059-023-02963-4 Genome Biology RESEARCH Open Access Genomic hallmarks and therapeutic implications of G0 cell cycle arrest in cancer Anna J. Wiecek1, Stephen J. Cutty2, Daniel Kornai1, Mario Parreno‑Centeno1, ...
Western blotting analysis showed that WPBFE could cause the arrest of cell cycle in G0/G1 phase by down-regulating expression levels of PCNA, CDK4, cyclin D1 and up-regulating the expression level of p21. Meanwh...
细胞周期（cell cycle）是指能持续分裂的真核细胞从一次有丝分裂完成到下一次分裂结束的循环过程，一般分...
We propose that the transition of quiescent stem cells into G(Alert) functions as an 'alerting' mechanism, an adaptive response that positions stem cells to respond rapidly under conditions of injury and stress, priming them for cell cycle entry. 参考文献:mTORC1 controls the adaptive transition ...
Inordertoinvestigatethemechanismsofterfenadine-inducedcellgrowtharrest,humancellstreatedwithterfenadineandtheresponseofgenesthatregulatedcellcycleweredetermined.Westernblotanalysisrevealedtheterfenadineresultsinaninductionofthep21、p27，andadown-regulationofCyclinD1、CyclinB、CDK2、CDK4.Theterfenadinetreatmentalsoresulted...
Cellgrowth and cell cycle progression were evaluated respectively by MTT assay and flow cytometry. ResultsElemene in-hibited the proliferation activity of U87MG and U251 glioblastoma cells, which showed time and dose- dependent, andincreased phosphorylation of both MKK3 and MKK6 in human glioblastoma...