Gamma-glutamyltransferase (GGT) is a liver enzyme, which is located on the plasma membranes of most cells and organ tissues, but more commonly in hepatocytes, and is routinely used in clinical practice to help indicate liver injury and as a marker of excessive alcohol consumption. Among the ...
These culture conditions allowed us to produce the highest amounts of GGT after about 150 h of culture. The GGT obtained from HepG2 cells was partially purified and some of its physico-chemical properties characterized. Successive Con A gel chromatography separated the activity into two peaks, ...
(CDAADD) and a purified choline-deficient diet (CDD) for rat liver were studied in terms of both 8-hydroxy-deoxyguanosine induction, a marker of DNA damage induced by oxidative stress, and development of -glutamyltransferase(GGT)-positive putative preneoplastic lesions, including foci an...